Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia.
Chem Commun (Camb). 2013 Apr 7;49(27):2816-8. doi: 10.1039/c3cc38330j.
Control of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.
通过限制击穿过程中的电流，实现了对 PDMS 介电击穿的控制。这使得能够调整纳米通道的孔径，从而调整不同分子量分子的渗透性。使用简单的一次性微流控装置，该方法能够在 3 分钟内从全血中分析药物奎宁。
