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儿童气管插管后声门下狭窄的发病率:前瞻性研究。

Incidence of post-intubation subglottic stenosis in children: prospective study.

作者信息

Schweiger C, Marostica P J Cauduro, Smith M M, Manica D, Carvalho P R Antonacci, Kuhl G

机构信息

Department of Otolaryngology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

出版信息

J Laryngol Otol. 2013 Apr;127(4):399-403. doi: 10.1017/S002221511300025X. Epub 2013 Feb 28.

Abstract

OBJECTIVE

To evaluate the incidence of subglottic stenosis in children undergoing endotracheal intubation.

METHODS

Children in the paediatric intensive care unit of a tertiary care hospital were considered eligible for inclusion if they received endotracheal intubation for more than 24 hours. After extubation, children underwent flexible fibre-optic nasolaryngoscopy. Based on this first evaluation, they were divided into two groups: 'acute normal', with mild laryngeal alterations or normal findings; and 'acute alterations', with moderate to severe laryngeal alterations. Further laryngoscopic follow up (7-10 days later) was undertaken for those children in the acute normal group who developed symptoms during follow up (after discharge from the intensive care unit), and for all children in the acute alterations group. Children were then classified into two final groups: 'normal final examination', with no chronic changes; and 'subglottic stenosis'.

RESULTS

We included 123 children. The incidence of subglottic stenosis was 11.38 per cent (95 per cent confidence interval, 6.63-17.94 per cent). All the children who developed subglottic stenosis had had moderate to severe alterations immediately after extubation.

CONCLUSION

This incidence of subglottic stenosis is quite high and needs further investigation to identify risk factors.

摘要

目的

评估接受气管插管的儿童声门下狭窄的发生率。

方法

在一家三级护理医院的儿科重症监护病房中,若儿童接受气管插管超过24小时,则被认为符合纳入标准。拔管后,儿童接受纤维鼻咽喉镜检查。根据首次评估结果,将他们分为两组:“急性正常组”,有轻度喉部改变或检查结果正常;“急性改变组”,有中度至重度喉部改变。对急性正常组中在随访期间(从重症监护病房出院后)出现症状的儿童,以及急性改变组的所有儿童,在7 - 10天后进行进一步的喉镜随访。然后将儿童分为两个最终组:“最终检查正常组”,无慢性改变;“声门下狭窄组”。

结果

我们纳入了123名儿童。声门下狭窄的发生率为11.38%(95%置信区间,6.63 - 17.94%)。所有发生声门下狭窄的儿童在拔管后立即都有中度至重度改变。

结论

这种声门下狭窄的发生率相当高,需要进一步研究以确定危险因素。

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