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翼板软骨移植对鼻阀塌陷伴鼻部过敏症状患者的鼻腔气道阻塞和鼻用类固醇使用的影响:一项前瞻性研究。

The effects of alar batten grafts on nasal airway obstruction and nasal steroid use in patients with nasal valve collapse and nasal allergic symptoms: a prospective study.

机构信息

Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology– Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN 46290, USA.

出版信息

JAMA Facial Plast Surg. 2013 May;15(3):182-6. doi: 10.1001/jamafacial.2013.974.

Abstract

IMPORTANCE

Clinical management of nasal airway obstruction (NAO) in patients with and without nasal allergic symptoms and nasal valve collapse (NVC).

OBJECTIVE

To examine the impact that autologous alar batten grafts have on patients with NAO owing to NVC and their affect on nasal steroid use and allergic symptoms.

DESIGN

A prospective study.

SETTING

Indiana University Medical Center, Indianapolis.

PARTICIPANTS

Patients with NAO due to NVC with or without symptoms of nasal allergic symptoms.

INTERVENTIONS

All of the patients had placement of autologous batten grafts during the study period.

STUDY SELECTION

Prospective study of patients with dynamic NVC undergoing alar batten graft treatment.

DATA EXTRACTION

Nasal Obstruction Symptom Evaluation survey preoperatively and postoperatively, prospective outpatient questionnaire to determine use of nasal steroids and presence of nasal allergic symptoms preoperatively and postoperatively.

RESULTS

A total of 126 patients underwent surgical intervention for the treatment of NAO due to NVC. All of these patients were using nasal steroid sprays, and 78 patients (62%) also reported nasal allergic symptoms at their initial presentation. At 6-month and 1-year postoperative evaluations, 118 (94%) and 122 (97%), respectively, reported significant improvement of their NAO, regardless if they had presented with or without allergic nasal symptoms. Sixty-two of the 78 patients (79%) who initially presented with NAO owing to NVC and nasal allergic symptoms preoperatively reported significant improvement in their NAO and nasal allergic symptoms postoperatively. Eight of 126 (6%) restarted their use of nasal steroids postoperatively. All 8 of these patients reported nasal allergic symptoms preoperatively. No patients in the nonallergic group continued the use of nasal steroids postoperatively. There was no increase in nasal steroid use at the 12-month follow-up visit.

CONCLUSIONS AND RELEVANCE

Nasal airway obstruction due to NVC in patients can be surgically treated with autologous alar batten grafts. In addition, the use of alar batten grafts may improve NAO in patients with nasal allergic symptoms and reduces their use of nasal steroids. These results support the idea of potential surgical repair of the nasal valve to treat patients with NAO due to nasal allergic symptoms and NVC.

LEVEL OF EVIDENCE

摘要

重要性

患有和不患有鼻过敏症状和鼻阀塌陷(NVC)的患者的鼻腔气道阻塞(NAO)的临床管理。

目的

检查自体鼻甲夹板移植对由于 NVC 导致的 NAO 患者的影响,以及对鼻腔类固醇使用和过敏症状的影响。

设计

前瞻性研究。

地点

印第安纳大学医学中心,印第安纳波利斯。

参与者

患有 NVC 引起的 NAO 且有或无鼻过敏症状的患者。

干预措施

所有患者在研究期间均接受自体鼻甲夹板移植。

研究选择

接受鼻甲夹板治疗的动态 NVC 患者的前瞻性研究。

数据提取

术前和术后进行鼻腔阻塞症状评估调查,前瞻性门诊问卷以确定术前和术后使用鼻腔类固醇和存在鼻过敏症状。

结果

共有 126 名患者因 NVC 导致的 NAO 接受了手术干预。所有这些患者都在使用鼻腔类固醇喷雾,并且 78 名患者(62%)在最初就诊时也报告了鼻过敏症状。在 6 个月和 1 年的术后评估中,分别有 118 名(94%)和 122 名(97%)患者报告其 NAO 有显著改善,无论他们是否有过敏的鼻部症状。在术前有 NVC 和鼻过敏症状的 78 名患者中,有 62 名(79%)报告其术后 NAO 和鼻过敏症状有显著改善。在 126 名患者中,有 8 名(6%)在术后重新开始使用鼻腔类固醇,这 8 名患者在术前均有鼻过敏症状。在非过敏组中,没有患者在术后继续使用鼻腔类固醇。在 12 个月的随访中,没有增加鼻腔类固醇的使用。

结论和相关性

NVC 导致的患者鼻腔气道阻塞可以通过自体鼻甲夹板移植进行手术治疗。此外,鼻甲夹板的使用可能会改善有鼻过敏症状的患者的 NAO,并减少他们对鼻腔类固醇的使用。这些结果支持通过手术修复鼻阀来治疗因鼻过敏症状和 NVC 导致的 NAO 的想法。

证据水平

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