Department of Internal Diseases, Medical Academy, Lithuanian University of Health Sciences, Eivenių 2, 50028 Kaunas, Lithuania.
Medicina (Kaunas). 2012;48(11):563-5.
Bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis that has been effectively used in the treatment of non-muscle invasive bladder carcinoma. The complications of this treatment are uncommon, and the causes of dissemination are still discussed. We report a case of disseminated tuberculosis in a 66-year-old smoking man without a history of pulmonary diseases, who underwent immunotherapy with BCG after the initial surgical treatment of bladder cancer. After the last BCG instillation, he developed a fever. The diagnosis of sepsis was not confirmed, and miliary pulmonary tuberculosis was suspected. The diagnosis was confirmed by clinical manifestation, computed tomography of the lungs, and histological examination.
卡介苗(BCG)是一株减毒的牛型分枝杆菌,已被有效地用于治疗非肌肉浸润性膀胱癌。这种治疗的并发症并不常见,其播散的原因仍在讨论中。我们报告了一例 66 岁吸烟男性的播散性结核病病例,该患者在膀胱癌初始手术治疗后接受了卡介苗免疫治疗。在最后一次 BCG 灌注后,他出现发热。未确诊脓毒症,疑似粟粒性肺结核。通过临床表现、肺部计算机断层扫描和组织学检查确诊。