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四价人乳头瘤病毒疫苗引入前后美国军人中尖锐湿疣的发病率

Incidence of genital warts among U.S. service members before and after the introduction of the quadrivalent human papillomavirus vaccine.

作者信息

Nsouli-Maktabi Hala, Ludwig Sharon L, Yerubandi Uma D, Gaydos Joel C

机构信息

Armed Forces Health Surveillance Center, Silver Spring, MD, USA.

出版信息

MSMR. 2013 Feb;20(2):17-20.

PMID:23461306
Abstract

Human papillomavirus (HPV) is the most common sexually transmitted infection among U.S. military members. The most frequent clinical manifestation of HPV is genital warts (GW). This investigation examined the annual incidence of diagnoses of GW among U.S. service members before and after the availability of the quadrivalent HPV (HPV4) vaccine in 2006. Incidence rates of GW diagnoses markedly declined among female service members in the HPV4 vaccine-eligible age range from 2007 (following introduction of the HPV4 vaccine) through 2010. In contrast, among women 25 years and older and men of all age groups, annual rates of GW diagnoses remained relatively low and stable from 2000 through 2010. The higher rates of diagnoses of GWs among female than male service members reflect the effects of routine periodic gynecologic screening. Slight increases in the incidence of GW diagnoses among men between 2010 and 2012 may in part reflect the repeal of the U.S. military's "Don't Ask Don't Tell" policy.

摘要

人乳头瘤病毒(HPV)是美国军人中最常见的性传播感染。HPV最常见的临床表现是尖锐湿疣(GW)。本研究调查了2006年四价HPV(HPV4)疫苗上市前后美国军人中GW诊断的年发病率。2007年(HPV4疫苗引入后)至2010年期间,符合HPV4疫苗接种条件年龄范围的女性军人中,GW诊断的发病率显著下降。相比之下,2000年至2010年期间,25岁及以上女性和所有年龄组男性的GW诊断年发病率保持相对较低且稳定。女性军人中GW诊断率高于男性,这反映了常规定期妇科筛查的影响。2010年至2012年期间男性中GW诊断发病率略有上升,这可能部分反映了美国军方“不问不说”政策的废除。

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