Cerrato Rebecca
Institute for Foot & Ankle Reconstruction, Mercy Medical Center, 301 St. Paul Place, Baltimore, MD 21202, USA.
Foot Ankle Clin. 2013 Mar;18(1):79-87. doi: 10.1016/j.fcl.2012.12.005.
Osteochondral lesions of the talus can present a challenge to the orthopedic surgeon. Because of its avascular nature, articular cartilage has a poor capacity for self-repair and regeneration. A wide variety of strategies have been developed to restore the structure and function of injured cartilage. Surgical strategies range from repair of cartilage through the formation of fibrocartilage to a variety of restorative procedures, including tissue-engineering-based strategies. A novel treatment option involves the implantation of particulated articular cartilage obtained from a juvenile allograft donor, the DeNovo NT graft. This article reviews the DeNovo NT graft, its usage, and surgical technique.
距骨的骨软骨损伤会给骨科医生带来挑战。由于关节软骨的无血管特性，其自我修复和再生能力较差。人们已经开发出各种各样的策略来恢复受损软骨的结构和功能。手术策略包括从通过形成纤维软骨来修复软骨到各种修复手术，包括基于组织工程的策略。一种新的治疗选择是植入从青少年同种异体移植供体获得的颗粒状关节软骨，即DeNovo NT移植物。本文综述了DeNovo NT移植物、其用法及手术技术。
