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[艾迪生病-比尔默氏病与自身免疫性甲状腺炎并存——病例报告]

[Coexistence of Addison-Biermer's disease with autoimmune thyroiditis - case report].

作者信息

Lacka Katarzyna, Maciejewski Adam, Florczak-Wyspiańska Jolanta

机构信息

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.

出版信息

Pol Merkur Lekarski. 2013 Jan;34(199):40-4.

Abstract

Addison-Biermer's anaemia is an autoimmune disease and the most common cause of vitamin B12 deficiency. Hashimoto disease is the most common type of the thyroiditis and also has autoimmunological origin. Frequent coexistence of both mentioned entities has been observed. In the paper we report a case of a woman, who was diagnosed with pernicious anaemia (PA) with predominant neurological symptoms and concomitant autoimmune thyroiditis. Many efforts have been made in order to explain frequent coexistence of mentioned diseases. Both genetic (mainly HLA region genes) and environmental (mostly bacterial infections) factors are considered. The aim of the study (was to emphasize significance of diagnosing thyroid gland diseases among PA patients. It is also important to remember that neurological symptoms are frequent in the course of PA and may precede other complaints. However it should not prevent the right diagnosis.

摘要

艾迪生-比尔默贫血是一种自身免疫性疾病,也是维生素B12缺乏的最常见原因。桥本氏病是甲状腺炎最常见的类型,也起源于自身免疫。已观察到上述两种病症经常并存。在本文中,我们报告了一例女性病例,该女性被诊断为以神经症状为主的恶性贫血(PA)并伴有自身免疫性甲状腺炎。为了解释上述疾病的频繁并存,人们已经做了很多努力。遗传因素(主要是HLA区域基因)和环境因素(主要是细菌感染)都被考虑在内。本研究的目的是强调在PA患者中诊断甲状腺疾病的重要性。同样重要的是要记住,神经症状在PA病程中很常见,可能先于其他症状出现。然而,这不应妨碍做出正确的诊断。

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