Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Pb 4956 Nydalen, N-0424 Oslo, Norway.
Resuscitation. 2013 Sep;84(9):1203-7. doi: 10.1016/j.resuscitation.2013.03.010. Epub 2013 Mar 15.
Optimal hand position for chest compressions during cardiopulmonary resuscitation is unknown. Recent imaging studies indicate significant inter-individual anatomical variations, which might cause varying haemodynamic responses with standard chest compressions. This prospective clinical pilot study intended to assess the feasibility of utilizing capnography to optimize chest compressions and identify the optimal hand position.
Intubated cardiac arrest patients treated by the physician manned ambulance between February and December 2011 monitored with continuous end-tidal CO2 (EtCO2) measurements were included. One minute of chest compressions at the inter-nipple line (INL) optimized using EtCO2 feedback, was followed by four 30-s intervals with compressions at four different sites; INL, 2 cm below the INL, 2 cm below and to the left of INL and 2 cm below and to the right of INL.
Thirty patients were included. At the end of each 30-s interval median (range) EtCO2 was 3.1 kPa (0.7-8.7 kPa) at INL, 3.5 kPa (0.5-10.7) 2 cm below INL, 3.5 kPa (0.5-10.3 kPa) 2 cm below and to the left of INL, and 3.8 kPa (0.4-8.8 kPa) 2 cm below and to the right of INL (p=0.4). The EtCO2 difference within each subject between hand positions with maximum and minimum values varied between individuals from 0.2 to 3.4 kPa (median 0.9 kPa).
Monitoring and optimizing chest compressions using capnography was feasible. We could not demonstrate one superior hand position, but inter-individual differences suggest optimal hand position might vary significantly among patients.
心肺复苏期间进行胸外按压时,最佳手部位置尚不清楚。最近的影像学研究表明,个体之间存在明显的解剖差异,这可能导致标准胸外按压时出现不同的血液动力学反应。本前瞻性临床初步研究旨在评估使用呼气末二氧化碳 (EtCO2) 监测优化胸外按压并确定最佳手部位置的可行性。
纳入 2011 年 2 月至 12 月期间由配备医生的救护车治疗的气管插管心脏骤停患者,进行连续的呼气末 CO2(EtCO2)测量。在使用 EtCO2 反馈优化乳头连线(INL)位置的 1 分钟胸外按压后,进行 4 次 30 秒的间隔,在 4 个不同位置进行按压:INL、INL 下方 2cm、INL 下方和左侧 2cm 以及 INL 下方和右侧 2cm。
共纳入 30 例患者。在每个 30 秒间隔结束时,INL 处的中位数(范围)EtCO2 为 3.1kPa(0.7-8.7kPa),INL 下方 2cm 处为 3.5kPa(0.5-10.7kPa),INL 下方和左侧 2cm 处为 3.5kPa(0.5-10.3kPa),INL 下方和右侧 2cm 处为 3.8kPa(0.4-8.8kPa)(p=0.4)。每个患者的每个手部位置之间的 EtCO2 差值(最大和最小)在个体之间变化范围为 0.2 至 3.4kPa(中位数 0.9kPa)。
使用呼气末二氧化碳监测来监测和优化胸外按压是可行的。我们无法证明一种手部位置具有优越性,但个体间的差异表明,最佳手部位置可能在患者之间存在显著差异。