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采用新型Y形单封堵带覆膜金属气道支架治疗右支气管胸膜瘘。

Right bronchopleural fistula treated with a novel, Y-shaped, single-plugged, covered, metallic airway stent.

作者信息

Wu Gang, Li Zong-Ming, Han Xin-Wei, Wang Zhong-Gao, Lu Hui-Bin, Zhu Ming, Ren Ke-Wei

机构信息

Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Acta Radiol. 2013 Jul;54(6):656-60. doi: 10.1177/0284185113481596. Epub 2013 Apr 30.

Abstract

BACKGROUND

Bronchopleural fistula (BPF) is an infrequent but life-threatening complication after pneumonectomy. The incidence of BPF reported in the literature varies from 0.3% to 20%.

PURPOSE

To determine the feasibility and efficacy of using Y-shaped, single-plugged, covered, metallic stents to treat right bronchopleural fistulas.

MATERIAL AND METHODS

We have designed a Y-shaped, single-plugged, covered, self-expandable, metallic airway stent to fit the specific anatomy of the right main bronchus. The stent has a main tube and two branches, resembling an inverted "Y". One of the branches is closed (plugged) and bullet-shaped; the other one tubular and open. The entire stent is encased in a nitinol wire mesh. Stent size can be individualized using multislice spiral computed tomography (MSCT) measurements of the airways. Under fluoroscopic guidance, we have implanted 15 Y-shaped stents in 15 patients with right bronchopleural fistulas.

RESULTS

Stent insertion was successful in all patients. All fistulas were successfully closed immediately after stent placement. Follow-up was performed for 1-34 months. Positive clinical outcomes were seen in 13 of 15 patients. Two patients died of intractable pulmonary infection and multiorgan failure. The fistula completely healed and the stent could be removed in five patients; however, two of them were left with a small, aseptic, residual right lung cavity. The remaining eight patients are still alive with the stent in situ.

CONCLUSION

The placement of Y-shaped, single-plugged, covered, self-expandable metallic airway stents seems to be a feasible and safe method for the treatment of bronchopleural fistulas involving the right main bronchus. This stent is a promising therapeutic alternative for bronchopleural fistulas involving the right main bronchus.

摘要

背景

支气管胸膜瘘(BPF)是肺切除术后一种罕见但危及生命的并发症。文献报道的BPF发生率在0.3%至20%之间。

目的

确定使用Y形、单封堵、覆膜金属支架治疗右支气管胸膜瘘的可行性和疗效。

材料与方法

我们设计了一种Y形、单封堵、覆膜、自膨式金属气道支架,以适应右主支气管的特定解剖结构。该支架有一个主管和两个分支,类似倒置的“Y”形。其中一个分支是封闭(封堵)的子弹形;另一个是管状且开放的。整个支架包裹在镍钛诺丝网中。可使用气道的多层螺旋计算机断层扫描(MSCT)测量结果来个体化定制支架尺寸。在荧光透视引导下,我们为15例右支气管胸膜瘘患者植入了15个Y形支架。

结果

所有患者支架植入均成功。支架置入后所有瘘口均立即成功闭合。随访1至34个月。15例患者中有13例临床结果良好。2例患者死于顽固性肺部感染和多器官功能衰竭。5例患者瘘口完全愈合且支架可取出;然而,其中2例患者右肺仍残留一个小的无菌腔隙。其余8例患者带支架存活。

结论

放置Y形、单封堵、覆膜、自膨式金属气道支架似乎是治疗累及右主支气管的支气管胸膜瘘的一种可行且安全的方法。该支架是治疗累及右主支气管的支气管胸膜瘘的一种有前景的治疗选择。

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