Humeau B, Cloarec D, Simon J, Bruley des Varannes S, Le Bodic L, Bouhour J B, Galmiche J P
Laboratoire d'Explorations Fonctionnelles Digestives, CHU Nord, Nantes.
Gastroenterol Clin Biol. 1990;14(4):334-41.
In patients with angina-like chest pain, the diagnostic value of esophageal investigations has not been definitively established. The aim of this study was to assess the diagnostic value of different esophageal investigations in 45 patients (group I) with angina-like chest pain for which a cardiac origin had been previously excluded. These investigations included esophageal manometry, Bernstein test, edrophonium test, balloon distention test, and 24-hour pH monitoring (with event marker). These patients were compared to two control groups: a) 9 subjects with documented coronary disease (group IIa), and b) 9 healthy volunteers (group IIb). Abnormal results were observed in 37 patients in group I (82 percent), and in 4 patients in group IIa (44 percent). In group I, manometry was abnormal in 29 percent of patients and pH monitoring in 41 percent; provocative tests were positive in 10 percent, 15 percent, and 38 percent for the Bernstein test, edrophonium test, and balloon distention test respectively. Esophageal origin of the pain was shown to be likely in 36 percent of patients in group I. These results confirm the high incidence of functional abnormalities of esophagus in patients with angina-like chest pain. They also confirm the diagnostic value of the different provocative tests and especially the balloon distention test.
在患有心绞痛样胸痛的患者中,食管检查的诊断价值尚未明确确立。本研究的目的是评估45例先前已排除心脏病因的心绞痛样胸痛患者(第一组)中不同食管检查的诊断价值。这些检查包括食管测压、伯恩斯坦试验、依酚氯铵试验、气囊扩张试验和24小时pH监测(带有事件标记)。将这些患者与两个对照组进行比较:a)9例有冠心病记录的受试者(第二组a),以及b)9名健康志愿者(第二组b)。第一组37例患者(82%)和第二组a 4例患者(44%)观察到异常结果。在第一组中,29%的患者测压异常,41%的患者pH监测异常;伯恩斯坦试验、依酚氯铵试验和气囊扩张试验的激发试验阳性率分别为10%、15%和38%。第一组中36%的患者疼痛可能源于食管。这些结果证实了心绞痛样胸痛患者食管功能异常的高发生率。它们还证实了不同激发试验的诊断价值,尤其是气囊扩张试验。