Guntani Atsushi, Okadome Jyun, Kawakubo Eisuke, Kyuragi Ryoichi, Iwasa Kazuomi, Fukunaga Ryota, Kuma Sosei, Matsumoto Takuya, Okazaki Jin, Maehara Yoshihiko
Department of Vascular Surgery, Kokura Memorial Hospital, Kitakyushu, Fukuoka, Japan.
Ann Vasc Dis. 2012;5(2):166-71. doi: 10.3400/avd.oa.11.00094.
Chronic renal insufficiency may be a relative contraindication to endovascular aneurysm repair (EVAR) for the use of contrast enhanced mediums. It is thought that more contrast enhanced media are needed in patients who are not anatomically suitable for EVAR, because of procedural difficulties. We reviewed a 2 year EVAR experience at our institution to determine whether the procedure and use of contrast enhanced mediums has any deleterious effect on renal function in patients with pre-existing chronic renal insufficiency.
EVAR was performed in 46 patients with pre-existing chronic renal insufficiency without hemodialysis. Patients were retrospectively assigned to two groups on the basis of their preoperative creatinine clearance levels. Furthermore, patients were assigned to two other groups on the basis of anatomical suitability for EVAR. The absolute change in the serum creatinine (Cr) level was reviewed in the each renal insufficiency group between the preoperative and post-operative time periods.
No increase in the serum Cr level was noted, and no patient required temporary or permanent hemodialysis, in any of the groups.
EVAR with contrast agents can be accomplished in patients with chronic renal insufficiency without hemodialysis; therefore,elevated Cr levels maynot be a contraindication in EVAR.
由于使用造影剂,慢性肾功能不全可能是血管内动脉瘤修复术(EVAR)的相对禁忌证。据认为,对于解剖结构不适合EVAR的患者,由于手术难度较大,需要更多的造影剂。我们回顾了我院两年的EVAR经验,以确定该手术及造影剂的使用对已存在慢性肾功能不全患者的肾功能是否有任何有害影响。
对46例未进行血液透析的慢性肾功能不全患者进行了EVAR手术。根据患者术前肌酐清除率水平,将患者回顾性地分为两组。此外,根据患者对EVAR的解剖学适应性,将患者分为另外两组。在每个肾功能不全组中,回顾术前和术后血清肌酐(Cr)水平的绝对变化。
在任何一组中,均未观察到血清Cr水平升高,也没有患者需要临时或永久性血液透析。
未进行血液透析的慢性肾功能不全患者可以进行使用造影剂的EVAR手术;因此,Cr水平升高可能不是EVAR的禁忌证。