索拉非尼成功治疗隆突性皮肤纤维肉瘤（DFSP）：病例报告
Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report.
作者信息
Kamar Francois G, Kairouz Victor F, Sabri Alain N
机构信息
Division of Hematology & Oncology, Clemenceau Medical Center, City Center Building, Suite 3 A, Avenue Nouvelle, P,O, Box 1076, Beirut, Jounieh, Lebanon.
出版信息
Clin Sarcoma Res. 2013 Apr 4;3(1):5. doi: 10.1186/2045-3329-3-5.
DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but was successfully treated with Sorafenib, which showed unprecedented response.
隆突性皮肤纤维肉瘤是一种皮下组织的局部侵袭性、生长缓慢的肿瘤，很少发生转移，但手术切除后常复发。我们在此报告一例高度复发性、局部侵袭性隆突性皮肤纤维肉瘤病例，该病例术后放疗及伊马替尼全程治疗均失败，但使用索拉非尼成功治疗，且显示出前所未有的反应。
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