Parihar Ajay, Newaskar Vilas
Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India.
Dent Res J (Isfahan). 2012 Nov;9(6):821-5.
Eosinophilic granuloma is a rare disease which is difficult to diagnose clinically and radiographically. Localized Langerhans' cell histiocytosis, previously known as eosinophilic granuloma, mainly affects the skull, mandible, vertebrae, pelvis and ribs in children and the long bones of adults. We present a case report of a female who developed pain and swelling over the left mandibular region, and was later diagnosed as eosinophilic granuloma, which after administration of intralesional corticosteroid with surgical enucleation showed positive response. This disease is of importance to dental professionals because early clinical signs can occur in the jaw and can cause extensive destruction of the periodontal tissues and bone. The purpose of this case report is to describe a case of eosinophilic granuloma with emphasis on conservative approach for the treatment and the radiographic changes observed during and after the treatment.
嗜酸性肉芽肿是一种罕见疾病,临床和影像学诊断均较为困难。局限性朗格汉斯细胞组织细胞增多症,以前称为嗜酸性肉芽肿,主要影响儿童的颅骨、下颌骨、椎骨、骨盆和肋骨以及成人的长骨。我们报告一例女性病例,该患者左侧下颌区域出现疼痛和肿胀,后来被诊断为嗜酸性肉芽肿,经病灶内注射皮质类固醇并手术摘除后显示出阳性反应。这种疾病对牙科专业人员很重要,因为早期临床症状可能出现在颌骨,可导致牙周组织和骨骼的广泛破坏。本病例报告的目的是描述一例嗜酸性肉芽肿病例,重点是保守治疗方法以及治疗期间和治疗后观察到的影像学变化。