基因组方法治疗慢性淋巴细胞白血病。
Genomic approaches to chronic lymphocytic leukemia.
机构信息
Department of Medical Oncology, Dana-Farber Cancer Institute, CLL Center, Harvard Medical School, Boston, MA 02215, USA.
出版信息
Hematol Oncol Clin North Am. 2013 Apr;27(2):157-71. doi: 10.1016/j.hoc.2013.01.001.
Abstract
This article discusses recent advances in genomic approaches used to understand chronic lymphocytic leukemia. Tools for analyzing DNA-level lesions are described, data obtained from these various platforms summarized, and the clinical relevance of these findings discussed.
摘要
本文讨论了用于了解慢性淋巴细胞白血病的基因组方法的最新进展。描述了用于分析 DNA 水平损伤的工具，总结了来自这些不同平台的数据，并讨论了这些发现的临床相关性。
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High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations.
Blood. 2012 Dec 6;120(24):4783-94. doi: 10.1182/blood-2012-04-423517. Epub 2012 Oct 9.
2
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.
Blood. 2012 Jul 26;120(4):843-6. doi: 10.1182/blood-2012-03-413591. Epub 2012 Jun 13.
3
Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia.
Clin Cancer Res. 2012 Jul 15;18(14):3791-802. doi: 10.1158/1078-0432.CCR-11-2342. Epub 2012 May 23.
4
Germline copy number variation associated with Mendelian inheritance of CLL in two families.
Leukemia. 2012 Jul;26(7):1710-3. doi: 10.1038/leu.2012.33. Epub 2012 Feb 7.
5
Post-GWAS functional characterization of susceptibility variants for chronic lymphocytic leukemia.
PLoS One. 2012;7(1):e29632. doi: 10.1371/journal.pone.0029632. Epub 2012 Jan 3.
6
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia.
Nat Genet. 2011 Dec 11;44(1):47-52. doi: 10.1038/ng.1032.
7
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.
N Engl J Med. 2011 Dec 29;365(26):2497-506. doi: 10.1056/NEJMoa1109016. Epub 2011 Dec 12.
8
Frequent pathway mutations of splicing machinery in myelodysplasia.
Nature. 2011 Sep 11;478(7367):64-9. doi: 10.1038/nature10496.
9
The prognostic significance of various 13q14 deletions in chronic lymphocytic leukemia.
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10
Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia.
Blood. 2011 Sep 15;118(11):3051-61. doi: 10.1182/blood-2010-12-327858. Epub 2011 Jul 27.
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