Department of Otolaryngology/Head and Neck Surgery, School of Medicine, Ehime University, Toon City, Ehime, Japan.
Ultrasound Med Biol. 2013 Jul;39(7):1178-83. doi: 10.1016/j.ultrasmedbio.2013.02.001. Epub 2013 Apr 3.
The aim of this study was to compare lymph node stiffness using acoustic radiation force impulse (ARFI) imaging in patients with cervical lymph node swelling. Forty-two cervical lymph nodes (reactive, n = 22; metastatic, n = 20) from 19 patients (13 men, 6 women; mean age, 63.68 ± 14.9 y; range, 23-85 y) were examined between September 2011 and March 2012. The shear wave velocity (SWV, m/s) of each lymph node was evaluated by ARFI imaging. SWV of reactive lymph nodes was 1.52 ± 0.48 m/s, and that of metastatic/malignant lymph nodes was 2.46 ± 0.75 m/s. A SWV > 1.9 m/s was very useful metastatic lymph node classification, with 95.0% specificity, 81.8% sensitivity and 88.0% overall accuracy. The area under the receiver operating characteristic curve was 0.923 (95% confidence interval, 0.842-1.000). ARFI imaging can be useful in the differentiation of reactive and malignant/metastatic cervical lymph nodes.
本研究旨在比较使用声辐射力脉冲(ARFI)成像技术评估颈部淋巴结肿大患者的淋巴结硬度。 2011 年 9 月至 2012 年 3 月,对 19 名患者(13 名男性,6 名女性;平均年龄 63.68 ± 14.9 岁;年龄范围 23-85 岁)的 42 个颈部淋巴结(反应性,n = 22;转移性,n = 20)进行了检查。 使用 ARFI 成像技术评估每个淋巴结的剪切波速度(SWV,m/s)。反应性淋巴结的 SWV 为 1.52 ± 0.48 m/s,转移性/恶性淋巴结的 SWV 为 2.46 ± 0.75 m/s。SWV > 1.9 m/s 是非常有用的转移性淋巴结分类,特异性为 95.0%,敏感性为 81.8%,总准确率为 88.0%。受试者工作特征曲线下面积为 0.923(95%置信区间,0.842-1.000)。ARFI 成像技术可用于区分反应性和恶性/转移性颈部淋巴结。