手性琥珀酰亚胺的动态结晶不对称转变。

Asymmetric transformation by dynamic crystallization of achiral succinimides.

机构信息

Department of Applied Chemistry and Biotechnology, Graduate School Engineering, Chiba University, Chiba-shi, Chiba 263-8522, Japan.

出版信息

Chem Commun (Camb). 2013 May 25;49(42):4776-8. doi: 10.1039/c3cc41678j.

DOI:10.1039/c3cc41678j

PMID:23591969

Abstract

Optically active materials could be generated by simple solidification of achiral materials without an external chiral source. When achiral cis-3,4-diphenylsuccinimides were solidified in the presence of a catalytic amount of DBU by evaporating the solvent with stirring, optically active trans-3,4-diphenylsuccinimides were obtained quantitatively with high enantiomeric excesses.

摘要

光学活性材料可以通过简单的无外消旋源的非手性物质固化来生成。当非手性顺式-3,4-二苯基琥珀酰亚胺在搅拌下蒸发溶剂的同时，用催化量的 DBU 固化时，定量得到具有高对映过量的光学活性反式-3,4-二苯基琥珀酰亚胺。