Ruiz-Iban M A, Díaz-Heredia J, Elías-Martín M E, Martos-Rodríguez L A, Cebreiro-Martínez del Val I, Pascual-Martín-Gamero F J
Departamento de Traumatología y Cirugía Ortopédica, Hospital Ramón y Cajal, Madrid, España.
Rev Esp Cir Ortop Traumatol. 2012 Jul-Aug;56(4):328-37. doi: 10.1016/j.recot.2012.04.002. Epub 2012 Jun 2.
Venous thromboembolism events (VTE) prophylaxis after elective hip or knee replacement surgery is a subject of controversy. Three sets of guidelines (NICE, ACCP and AAOS) on this topic have recently been updated. The guidelines have points in common: prophylaxis is necessary, it is recommended to combine mechanical and pharmacological prophylaxis in patients who have suffered a previous VTE, isolated mechanical measures and low molecular weight heparins are effective, the new oral anticoagulants and fondaparinux are effective drugs. There is some consensus in recommending regional anaesthesia, in advising against echography studies in asymptomatic patients, and in the promotion of early mobilisation of the patient. There is controversy over the most suitable pharmacological treatment and the time of starting, and the duration of this, as well as on vena cava filters, antiplatelet drugs, and VTE or bleeding risk factors.
择期髋关节或膝关节置换手术后的静脉血栓栓塞事件(VTE)预防是一个有争议的话题。关于这一主题的三套指南(英国国家卫生与临床优化研究所、美国胸科医师学会和美国骨科学会)最近已经更新。这些指南有一些共同点:预防是必要的,对于既往发生过VTE的患者,建议联合使用机械性和药物性预防措施,单纯的机械措施和低分子肝素是有效的,新型口服抗凝药和磺达肝癸钠是有效的药物。在推荐区域麻醉、不建议对无症状患者进行超声检查以及促进患者早期活动方面存在一些共识。在最合适的药物治疗及其开始时间、持续时间,以及腔静脉滤器、抗血小板药物和VTE或出血风险因素方面存在争议。