Grimm F, Ebner F H, Honegger J
Klinik für Neurochirurgie, Universitätsklinikum Tübingen, Tübingen.
Ophthalmologe. 2013 May;110(5):421-6. doi: 10.1007/s00347-012-2704-y.
Meningiomas are the most common form of primary intracranial tumors. If the anterior visual pathways are affected clinical visual compromise, visual field defects, oculomotor nerve disturbances or propotosis are predominant. Meningiomas of the anterior visual pathway remain therapeutically challenging due to the direct anatomical relationship to the circulus arteriosus cerebri, the cavernous sinus and cranial nerves. The therapy of choice is microsurgical resection. In many cases a curative approach can be achieved with modern surgical techniques and simultaneously maintaining patient quality of life. Problematic are cases in which resection would be associated with the risk of clinical impairment and in these cases radiotherapy is an important therapeutic option. In cases involving complex invasiveness an interdisciplinary treatment to control local clinical symptoms is favored.
脑膜瘤是原发性颅内肿瘤最常见的形式。如果前视觉通路受到影响,临床视觉损害、视野缺损、动眼神经紊乱或眼球突出较为常见。由于前视觉通路脑膜瘤与大脑动脉环、海绵窦和颅神经存在直接的解剖关系,其治疗仍具有挑战性。首选治疗方法是显微手术切除。在许多情况下,采用现代手术技术可以实现治愈性治疗,同时维持患者的生活质量。存在问题的是那些切除手术会伴有临床功能受损风险的病例,在这些情况下,放射治疗是重要的治疗选择。对于涉及复杂侵袭性的病例,倾向于采用多学科治疗来控制局部临床症状。