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[来自已故捐赠者肝脏的分配:当前分配规则与算法]

[Distribution of livers from deceased donors : current allocation rules and algorithms].

作者信息

Rahmel A

机构信息

Eurotransplant International Foundation und Universität Gent, 2301 CH, Leiden, Niederlande.

出版信息

Chirurg. 2013 May;84(5):372-9. doi: 10.1007/s00104-012-2417-4.

Abstract

Eurotransplant is responsible for the allocation of organs from deceased donors in Germany. The guidelines governing this allocation process have been developed and are continuously updated by the German Medical Association and are based on urgency and outcome of the planned transplantation. The allocation sequence for donor livers is based on the model of end-stage liver disease (MELD) score, which is calculated using three laboratory values, bilirubin, creatinine and the international normalized ratio (INR) and allows an objective and transparent evaluation of the urgency of the transplantation. For patients with liver diseases where the MELD score does not allow an estimation of the urgency of the transplantation, special rules apply. The international cooperation among the Eurotransplant member countries especially increases the probability of finding a suitable donor organ in time for highly urgent patients and patients with special difficulties in matching characteristics.

摘要

欧洲器官移植组织负责德国已故捐赠者器官的分配。德国医学协会制定并不断更新了指导这一分配过程的准则,这些准则基于计划移植的紧迫性和结果。供体肝脏的分配顺序基于终末期肝病(MELD)评分模型,该评分通过胆红素、肌酐和国际标准化比值(INR)这三项实验室值计算得出,能够对移植的紧迫性进行客观、透明的评估。对于MELD评分无法评估移植紧迫性的肝病患者,适用特殊规则。欧洲器官移植组织成员国之间的国际合作尤其提高了为高度紧急患者和匹配特征存在特殊困难的患者及时找到合适供体器官的概率。

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