Shukla Shyamji, Shukla Harshita, Kumar Suneel, Aharwal Ravindra P, Gupta Vaibhav K, Sandhu Sardul S
Fungal Biotechnology and Invertebrate Pathology Laboratory, Department of Biological Sciences, Rani Durgawati University Jabalpur- 482001, M.P. India.
Recent Pat Inflamm Allergy Drug Discov. 2013 May;7(2):135-50. doi: 10.2174/1872213x11307020005.
All organisms are protected by their immune system but occasionally this system overreacts leading to allergic and inflammatory reactions in the body. These reactions are the starting points of various diseases like asthma, eczema and urticaria etc. They involve activation of T cells, release of histamines, toxic chemicals from mast cells and eosinophils respectively. Several chemically and naturally synthesized therapeutic agents are available for the treatment of these immunological diseases. The present review provides a detailed account of mechanism of allergic and inflammatory reactions, its types and various treatment strategies with a special focus on some recent patents in this field.
所有生物体都受到其免疫系统的保护，但该系统偶尔会过度反应，导致体内出现过敏和炎症反应。这些反应是哮喘、湿疹和荨麻疹等各种疾病的起始点。它们分别涉及T细胞的激活、组胺的释放、肥大细胞和嗜酸性粒细胞释放的有毒化学物质。有几种化学合成和天然合成的治疗剂可用于治疗这些免疫性疾病。本综述详细阐述了过敏和炎症反应的机制、其类型以及各种治疗策略，并特别关注了该领域的一些最新专利。
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