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择期宫颈环扎术后妊娠结局与缝线材料类型的关系。

Pregnancy outcome after elective cervical cerclage in relation to type of suture material used.

机构信息

Birmingham Women's Hospital NHS Foundation Trust, Mindelsohn Way, Edgbaston, Birmingham B15 2TG, United Kingdom.

出版信息

Med Hypotheses. 2013 Jul;81(1):119-21. doi: 10.1016/j.mehy.2013.04.003. Epub 2013 Apr 28.

Abstract

Cervical weakness is an important cause of late miscarriage and extreme preterm labour. Women have been traditionally offered a cervical cerclage procedure, though studies failed to demonstrate a therapeutic effect. None of these studies has addressed the effect of non-braided to braided suture material on cerclage outcome. Type of suture material is an important determinant of surgical outcomes. This issue is of particular relevance to cerclage because the traditionally braided suture has been associated with increased risk of infection in other surgical procedures. Indeed, infection is an important underlying cause for cerclage failure. It is for this reason that some surgeons use non-braided suture material. Therefore, we hypothesise that the unrealised benefit of cervical cerclage is at least in part due to the type of suture material used. In this article, we present the rationale behind our hypothesis and a proposed way of testing it.

摘要

宫颈机能不全是晚期流产和极早产的重要原因。传统上,女性会接受宫颈环扎术,但研究未能证明其治疗效果。这些研究都没有涉及缝线材料是编织线还是非编织线对环扎术结果的影响。缝线材料的类型是手术结果的重要决定因素。这个问题对于环扎术尤为重要,因为传统的编织缝线与其他手术程序中的感染风险增加有关。事实上,感染是环扎术失败的一个重要潜在原因。正是出于这个原因,一些外科医生使用非编织缝线材料。因此,我们假设宫颈环扎术未实现的益处至少部分归因于所使用的缝线材料类型。在本文中,我们介绍了我们假设背后的基本原理以及一种可能的检验方法。

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