Royal National Orthopaedic Hospital, Peripheral Nerve Unit, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK.
Bone Joint J. 2013 May;95-B(5):699-705. doi: 10.1302/0301-620X.95B5.30948.
We investigated the predictive value of intra-operative neurophysiological investigations in obstetric brachial plexus injuries. Between January 2005 and June 2011 a total of 32 infants of 206 referred to our unit underwent exploration of the plexus, including neurolysis. The findings from intra-operative electromyography, sensory evoked potentials across the lesion and gross muscular response to stimulation were evaluated. A total of 22 infants underwent neurolysis alone and ten had microsurgical reconstruction. Of the former, one was lost to follow-up, one had glenoplasty and three had subsequent nerve reconstructions. Of the remaining 17 infants with neurolysis, 13 (76%) achieved a modified Mallet score > 13 at a mean age of 3.5 years (0.75 to 6.25). Subluxation or dislocation of the shoulder is a major confounding factor. The positive predictive value and sensitivity of the intra-operative EMG for C5 were 100% and 85.7%, respectively, in infants without concurrent shoulder pathology. The positive and negative predictive values, sensitivity and specificity of the three investigations combined were 77%, 100%, 100% and 57%, respectively. In all, 20 infants underwent neurolysis alone for C6 and three had reconstruction. All of the former and one of the latter achieved biceps function of Raimondi grade 5. The positive and negative predictive values, sensitivity and specificity of electromyography for C6 were 65%, 71%, 87% and 42%, respectively. Our method is effective in evaluating the prognosis of C5 lesion. Neurolysis is preferred for C6 lesions.
我们研究了术中神经生理学研究在产科臂丛神经损伤中的预测价值。2005 年 1 月至 2011 年 6 月,共有 206 例患儿转诊至我院行臂丛探查术,包括神经松解术。评估术中肌电图、病变处体感诱发电位和刺激下的粗大肌肉反应的结果。22 例患儿仅行神经松解术,10 例患儿行显微外科重建术。前者中 1 例失访,1 例行盂肱关节成形术,3 例行后续神经重建术。17 例行神经松解术的患儿中,13 例(76%)在平均 3.5 岁(0.75 至 6.25 岁)时获得改良 Mallet 评分>13。肩关节半脱位或脱位是一个主要的混杂因素。术中肌电图对 C5 的阳性预测值和灵敏度分别为 100%和 85.7%,在无并发肩部病变的患儿中。三种检查联合的阳性和阴性预测值、灵敏度和特异性分别为 77%、100%、100%和 57%。共 20 例患儿行 C6 神经松解术,3 例患儿行重建术。前者均和后者中的 1 例患儿获得二头肌 Raimondi 分级 5 级。肌电图对 C6 的阳性和阴性预测值、灵敏度和特异性分别为 65%、71%、87%和 42%。我们的方法可有效评估 C5 病变的预后。神经松解术是 C6 病变的首选治疗方法。