Natsakis Tassos, Peeters Koen, Burg Fien, Dereymaeker Greta, Vander Sloten Jos, Jonkers Ilse
Department of Mechanical Engineering, Faculty of Engineering KU Leuven, Belgium.
Proc Inst Mech Eng H. 2013 Apr;227(4):454-63. doi: 10.1177/0954411912464459. Epub 2012 Nov 23.
Until now, the methods used to set up in vitro gait simulations were not specimen specific, inflicting several problems when dealing with specimens of considerably different dimensions and requiring arbitrary parameter tuning of the control variables. We constructed a model that accounts for the geometric dimensions of the specimen and is able to predict the tibial kinematics during the stance phase. The model predicts tibial kinematics of in vivo subjects with very good accuracy. Furthermore, if used in in vitro gait simulation studies, it is able to recreate physiological vertical ground reaction forces. By using this methodology, in vitro studies can be performed by taking the specimen variability into account, avoiding pitfalls with specimens of different dimensions.
到目前为止，用于建立体外步态模拟的方法并非针对特定标本，在处理尺寸差异很大的标本时会产生一些问题，并且需要对控制变量进行任意参数调整。我们构建了一个考虑标本几何尺寸的模型，该模型能够预测站立期的胫骨运动学。该模型能非常准确地预测体内受试者的胫骨运动学。此外，如果用于体外步态模拟研究，它能够重现生理垂直地面反作用力。通过使用这种方法，可以在考虑标本变异性的情况下进行体外研究，避免不同尺寸标本带来的问题。
