Zefirov A L, Khalilov I A
Biull Eksp Biol Med. 1990 Mar;109(3):219-22.
In experiments on the frog cutaneous-pectoris muscle under the visual control the evoked responses of nerve endings were recorded in proximal, central and distal parts of the terminal. At the fixed position of the recording electrode the local iontophoretic application of TTX to different terminal parts and Ranvier's nodes was performed. It was concluded, that local currents at more proximal terminal parts provide the depolarization of the located parts and conduction of excitation to the nonexcitable parts. Inward currents at behind located and already excited parts are shortened and decreased by local currents from more distal parts during the propagation of excitation. It results in shortening of the action potential and decreasing of the transmitter release in more proximal parts. This effect disappeared along the nerve terminal due to decreasing of inward Na current at the end parts.
在视觉控制下对青蛙胸皮肌进行的实验中，记录了神经末梢在终末的近端、中部和远端部分的诱发反应。在记录电极固定位置的情况下，对不同的终末部分和郎飞结进行了局部离子电渗法施加河豚毒素（TTX）的操作。得出的结论是，在终末更靠近近端的部分，局部电流使所定位部分发生去极化，并将兴奋传导至非兴奋部分。在兴奋传播过程中，位于后方且已兴奋部分的内向电流会被来自更远端部分的局部电流缩短和减弱。这导致动作电位缩短以及在更靠近近端的部分递质释放减少。由于终末部分内向钠电流的减少，这种效应沿神经末梢消失。
