Department of Vascular and Endovascular Surgery, Klinikum Nürnberg, Germany.
Eur J Vasc Endovasc Surg. 2013 Jul;46(1):49-56. doi: 10.1016/j.ejvs.2013.03.028. Epub 2013 May 1.
To review our experience with fenestrated endovascular aneurysm repair (F-EVAR) to treat complications after previous standard infrarenal endovascular aneurysm repair (EVAR).
A prospectively maintained database including all consecutive patients with juxtarenal abdominal aortic aneurysm that were treated with F-EVAR after failed previous EVAR within the period March 2002 to November 2012 at the University Medical Center of Groningen, Netherlands (up to October 2009), and the Klinikum Nürnberg Süd, Germany (from November 2009) was analyzed. Evaluated outcomes included initial technical success, operative mortality and morbidity, and late procedure-related events with regard to survival, target vessel patency, endoleak, renal function, and reintervention.
A total of 26 patients (24 male, mean age 73.2 ± 6.5 years) were treated. All patients had proximal anatomies precluding endovascular reintervention with standard techniques. In 23 patients a fenestrated proximal cuff was used, and in three patients a bifurcated fenestrated stent graft. Technical success was achieved in 24 (92.3%) patients. One patient required on-table open conversion because of impossibility to retrieve the top cap as a result of twist of the ipsilateral limb. In the second patient the right kidney was lost due to inadvertent stenting in a smaller branch of the renal artery. Catheterization difficulties, all related to the passage through the limbs or struts of the previous stent graft, were encountered in 11 (42.3%) cases, including five (19.2%) patients with iliac access problems and six (23.1%) with challenging renal catheterization. Operative target vessel perfusion success rate was 94.6% (70/74). Operative mortality was 0%. Mean follow-up was 26.8 ± 28.5 months. No proximal type I endoleak was present on first postoperative CTA. The mean aneurysm maximal diameter decreased from 73 ± 20 mm to 66.7 ± 21 mm (p < .05). There were six late deaths, one of them aneurysm related. Estimated survival rates at 1 and 2 years were 94.1 ± 5.7% and 87.4 ± 8.4%, respectively. Patency during follow-up for the target vessels treated successfully with a fenestrated stent graft was 100% (70/70). Reintervention was required in four cases, including one acute conversion due to rupture, one for iliac limb occlusion and two for type Ib and II endoleak. Renal function deterioration was observed solely in the two cases of primary technical failure.
F-EVAR represents a feasible option for the repair of juxtarenal abdominal aortic aneurysm after prior EVAR failure. It is advantageous in terms of mortality and less morbid than open surgery, but is associated with increased technical challenges because of the previously placed stent graft. Outcome seems related to initial technical success.
回顾我们在处理先前标准肾下腔内血管修复术(EVAR)后并发症时使用开窗式腔内血管修复术(F-EVAR)的经验。
分析 2002 年 3 月至 2012 年 11 月期间荷兰格罗宁根大学医疗中心(2009 年 10 月前)和德国纽伦堡南医院(2009 年 11 月后)对接受先前 EVAR 失败后行 F-EVAR 治疗的近肾腹主动脉瘤连续患者的前瞻性维护数据库。评估的结果包括初始技术成功率、手术死亡率和发病率,以及与生存、靶血管通畅、内漏、肾功能和再介入相关的晚期程序相关事件。
共治疗 26 例患者(24 例男性,平均年龄 73.2±6.5 岁)。所有患者近端解剖结构排除了使用标准技术进行腔内再干预的可能性。23 例患者使用了开窗式近端袖口,3 例患者使用了分叉式开窗支架移植物。24 例(92.3%)患者达到了技术成功。1 例患者因对侧支扭曲导致无法取回顶帽而需要在台上进行开放转换。在第二例患者中,右肾因误将支架置入肾动脉较小的分支而丢失。11 例(42.3%)患者在导管插入过程中遇到困难,均与先前支架移植物的支腿或支柱通过有关,包括 5 例(19.2%)髂内动脉入路问题和 6 例(23.1%)肾导管插入困难。手术目标血管灌注成功率为 94.6%(70/74)。手术死亡率为 0%。平均随访时间为 26.8±28.5 个月。第一次术后 CTA 未见近端 I 型内漏。动脉瘤最大直径从 73±20mm 降至 66.7±21mm(p<0.05)。有 6 例晚期死亡,其中 1 例与动脉瘤有关。1 年和 2 年的估计生存率分别为 94.1±5.7%和 87.4±8.4%。用开窗式支架移植物成功治疗的靶血管在随访期间通畅率为 100%(70/70)。4 例患者需要再次干预,包括 1 例因破裂导致急性转换,1 例因髂支闭塞,2 例因 I 型和 II 型内漏。仅在 2 例原发技术失败的患者中观察到肾功能恶化。
F-EVAR 是先前 EVAR 失败后修复近肾腹主动脉瘤的可行选择。它在死亡率方面优于开放手术,且更微创,但由于先前放置的支架移植物,技术挑战增加。结果似乎与初始技术成功率有关。