Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, United States.
Vaccine. 2013 Jun 19;31(28):2937-46. doi: 10.1016/j.vaccine.2013.04.041. Epub 2013 Apr 30.
Human papillomavirus (HPV) vaccination is recommended to protect against HPV-related diseases.
To estimate HPV vaccine coverage and assess factors associated with vaccine awareness, initiation and receipt of 3 doses among women age 18-30 years.
Data from the 2010 National Health Interview Survey were analyzed to assess associations of HPV vaccination among women age 18-26 (n=1866) and 27-30 years (n=1028) with previous HPV exposure, cervical cancer screening and selected demographic, health care and behavioral characteristics using bivariate analysis and multivariable logistic regression.
Overall, 23.2% of women age 18-26 and 6.7% of women age 27-30 years reported receiving at least 1 dose of HPV vaccine. In multivariable analyses among women age 18-26 years, not being married, having a regular physician, seeing a physician or obstetrician/gynecologist in the past year, influenza vaccination in the past year, and receipt of other recommended vaccines were associated with HPV vaccination. One-third of unvaccinated women age 18-26 years (n=490) were interested in receiving HPV vaccine. Among women who were not interested in receiving HPV vaccine (n=920), the main reasons reported included: not needing the vaccine (41.3%); concerns about safety of the vaccine (12.5%); not knowing enough about the vaccine (11.9%); not being sexually active (8.2%); a doctor not recommending the vaccine (7.6%); and already having HPV (2.7%). Among women with health insurance, 10 or more physician contacts within the past year and no contraindications, 74.5% reported not receiving HPV vaccine.
HPV vaccination coverage among women age 18-26 years remains low. Opportunities to vaccinate are missed. Healthcare providers can play an important role in educating young women about HPV and encouraging vaccination. Successful public health and educational interventions will need to address physician attitudes and practice patterns and other factors that influence vaccination behaviors.
人乳头瘤病毒（HPV）疫苗接种旨在预防 HPV 相关疾病。
估计 HPV 疫苗接种率，并评估 18-30 岁女性中 HPV 疫苗知晓率、起始接种率和接种 3 剂率的相关因素。
分析 2010 年全国健康访谈调查数据，采用双变量分析和多变量逻辑回归评估 18-26 岁（n=1866）和 27-30 岁（n=1028）女性 HPV 疫苗接种与 HPV 暴露、宫颈癌筛查和选定的人口统计学、医疗保健及行为特征的相关性。
总体而言，18-26 岁女性中有 23.2%，27-30 岁女性中有 6.7%报告至少接种过 1 剂 HPV 疫苗。在 18-26 岁女性的多变量分析中，未结婚、有常规医生、过去 1 年看医生或妇产科医生、过去 1 年接种流感疫苗和接种其他推荐疫苗与 HPV 疫苗接种相关。三分之一未接种 HPV 疫苗的 18-26 岁女性（n=490）表示有接种 HPV 疫苗的意愿。在不打算接种 HPV 疫苗的女性中（n=920），报告的主要原因包括：不需要接种疫苗（41.3%）；对疫苗安全性的担忧（12.5%）；对疫苗了解不够（11.9%）；没有性行为（8.2%）；医生不推荐接种疫苗（7.6%）；已经感染 HPV（2.7%）。在有医疗保险的女性中，过去 1 年内有 10 次或更多次与医生接触且无禁忌症的女性中，有 74.5%未接种 HPV 疫苗。
18-26 岁女性 HPV 疫苗接种率仍然较低。错过了接种疫苗的机会。医疗保健提供者在教育年轻女性了解 HPV 和鼓励接种疫苗方面可以发挥重要作用。成功的公共卫生和教育干预措施需要解决医生的态度和实践模式以及影响疫苗接种行为的其他因素。
