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Correlation between peripheral arterial disease and coronary artery disease using ankle brachial index-a study in Indian population.使用踝臂指数评估外周动脉疾病与冠状动脉疾病之间的相关性——一项针对印度人群的研究。
Indian Heart J. 2012 Jan-Feb;64(1):2-6. doi: 10.1016/S0019-4832(12)60002-9. Epub 2012 Mar 26.
2
Carotid intima-media thickness for the practicing lipidologist.颈动脉内膜中层厚度:临床血脂学家实践指南
J Clin Lipidol. 2010 Jan-Feb;4(1):24-35. doi: 10.1016/j.jacl.2009.11.004. Epub 2009 Dec 16.
3
The ankle-brachial index and incident cardiovascular events in the MESA (Multi-Ethnic Study of Atherosclerosis).踝臂指数与 MESA(动脉粥样硬化多民族研究)中的心血管事件。
J Am Coll Cardiol. 2010 Oct 26;56(18):1506-12. doi: 10.1016/j.jacc.2010.04.060.
4
Abnormal ankle brachial index and the presence of significant coronary artery disease.异常踝肱指数与显著冠状动脉疾病的存在。
J Coll Physicians Surg Pak. 2010 Feb;20(2):79-82.
5
Ankle brachial index as a prognostic tool for women with coronary artery disease.踝臂指数作为冠状动脉疾病女性患者的预后工具。
J Cardiovasc Nurs. 2010 Jan-Feb;25(1):20-4. doi: 10.1097/JCN.0b013e3181b7be4c.
6
Relationship between carotid intima-media thickness and coronary angiographic findings: a prospective study.颈动脉内膜中层厚度与冠状动脉造影结果之间的关系:一项前瞻性研究。
Cardiovasc Ultrasound. 2009 Dec 31;7:59. doi: 10.1186/1476-7120-7-59.
7
Usefulness of carotid intima-media thickness in patients with diabetes mellitus as a predictor of coronary artery disease.糖尿病患者颈动脉内膜中层厚度作为冠状动脉疾病预测指标的效用。
Am J Cardiol. 2009 Oct 15;104(8):1041-6. doi: 10.1016/j.amjcard.2009.06.004.
8
Association of carotid intima-media thickness with left main coronary artery disease.颈动脉内膜中层厚度与左主干冠状动脉疾病的关联。
Indian Heart J. 2007 Jan-Feb;59(1):50-5.
9
Carotid artery intima-media thickness is associated with coronary artery disease.颈动脉内膜中层厚度与冠状动脉疾病相关。
Acta Cardiol. 2008 Jun;63(3):309-13. doi: 10.2143/AC.63.3.1020306.
10
Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial.瑞舒伐他汀对亚临床动脉粥样硬化低风险个体颈动脉内膜中层厚度进展的影响:METEOR试验
JAMA. 2007 Mar 28;297(12):1344-53. doi: 10.1001/jama.297.12.1344. Epub 2007 Mar 25.

踝臂指数与颈动脉内膜中层厚度作为印度人严重冠状动脉粥样硬化替代标志物的诊断效用比较。

Comparison of diagnostic utilities of ankle-brachial index and carotid intima-media thickness as surrogate markers of significant coronary atherosclerosis in Indians.

作者信息

Ezhumalai Babu, Krishnasuri Subrahmanyam Dharanipragada, Jayaraman Balachander

机构信息

Senior Resident, Dept. of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Dhanvantri Nagar, Gorimedu, Pondicherry 605006, India.

出版信息

Indian Heart J. 2013 Mar-Apr;65(2):137-41. doi: 10.1016/j.ihj.2013.02.011. Epub 2013 Feb 21.

DOI:10.1016/j.ihj.2013.02.011
PMID:23647891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3861066/
Abstract

AIM

We aimed to compare Ankle-brachial index (ABI) and Carotid intima-media thickness (CIMT) as surrogate markers of significant coronary atherosclerosis in South Indians with coronary artery disease (CAD).

METHODS AND RESULTS

There were two groups: CAD group (n = 59) and Control group (n = 55). Mean ABI (0.82 ± 0.06 vs. 1.16 ± 0.11, p < 0.0001) and mean CIMT (0.74 ± 0.22 mm vs. 0.45 ± 0.09 mm, p < 0.0001) were statistically different between two groups. ABI < 0.9 (sensitivity: 91.53%, specificity: 100%) and CIMT > 0.63 mm (sensitivity: 61.02%, specificity: 98.18%) implied significant CAD. ABI and CIMT were negatively correlated to one another. With increasing severity of CAD, ABI decreased but CIMT increased.

CONCLUSION

ABI and CIMT are simple noninvasive tools providing insight into coronary atherosclerosis. They can be done at bedside and easily repeated than coronary angiography. ABI < 0.9 is a better surrogate marker of significant coronary atherosclerosis than CIMT > 0.63 mm in South Indians with CAD.

摘要

目的

我们旨在比较踝臂指数(ABI)和颈动脉内膜中层厚度(CIMT),将其作为患有冠状动脉疾病(CAD)的南印度人严重冠状动脉粥样硬化的替代标志物。

方法与结果

分为两组:CAD组(n = 59)和对照组(n = 55)。两组间的平均ABI(0.82±0.06对1.16±0.11,p < 0.0001)和平均CIMT(0.74±0.22毫米对0.45±0.09毫米,p < 0.0001)存在统计学差异。ABI < 0.9(敏感性:91.53%,特异性:100%)和CIMT > 0.63毫米(敏感性:61.02%,特异性:98.18%)提示存在严重CAD。ABI和CIMT彼此呈负相关。随着CAD严重程度增加,ABI降低而CIMT升高。

结论

ABI和CIMT是提供冠状动脉粥样硬化相关信息的简单无创工具。它们可在床边进行,且比冠状动脉造影更容易重复操作。在患有CAD的南印度人中,ABI < 0.9比CIMT > 0.63毫米是更优的严重冠状动脉粥样硬化替代标志物。