Zhang W Y
Second Teaching Hospital, Bethune University of Medical Sciences, Changchun.
Zhonghua Fu Chan Ke Za Zhi. 1990 Mar;25(2):95-7, 124-5.
The pregnancy-specific beta 1 glycoprotein (SP1) levels in the serum of normal and abnormal pregnancies were determined by radioimmunoassay in the first trimester. The results indicated that serum SP1 levels of normal pregnancies increased with the advancing gestational week; 67% of threatened abortions with low SP1 levels would finally abort and only 7% of those with normal SP1 levels would abort. Serum SP1 levels were of lower values in ectopic pregnancy and hydatidiform mole. Serum SP1 might be taken as a better index for estimating the fetal prognosis in threatened abortion and an auxiliary diagnostic means for ectopic pregnancy and hydatidiform mole.
在孕早期，采用放射免疫分析法测定正常妊娠和异常妊娠孕妇血清中妊娠特异性β1糖蛋白（SP1）水平。结果显示，正常妊娠孕妇血清SP1水平随孕周增加而升高；SP1水平低的先兆流产孕妇中，67%最终会流产，而SP1水平正常的先兆流产孕妇中只有7%会流产。异位妊娠和葡萄胎患者的血清SP1水平较低。血清SP1可作为评估先兆流产胎儿预后的较好指标，以及异位妊娠和葡萄胎的辅助诊断手段。
