Panciera R J, Martin T, Burrows G E, Taylor D S, Rice L E
Department of Veterinary Pathology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078.
J Am Vet Med Assoc. 1990 Jun 15;196(12):1981-4.
Ten of 100 mature ewes were afflicted with acute oxalate toxicosis within 40 hours after being temporarily penned in a lot that contained considerable growing Rumex crispus (curly dock). Clinical signs of toxicosis included excess salivation, tremors, ataxia, and recumbency. Affected ewes were markedly hypocalcemic and azotemic. Oxalate crystals were not observed in urine. Gross postmortem lesions were minimal and nondiagnostic in 2 ewes that died peracutely, but perirenal edema and renal tubular degeneration were clearly observable in ewes euthanatized on the third day of toxicosis. Diagnosis of oxalate toxicosis was confirmed by histopathologic findings. Samples of Rumex spp contained 6.6 to 11.1% oxalic acid on a dry-weight basis, a concentration comparable with that in other oxalate-containing plants that have caused acute oxalate toxicosis.
100只成年母羊中有10只在被临时圈养在一个生长着大量皱叶酸模(卷叶酸模)的围栏内40小时内患上急性草酸盐中毒。中毒的临床症状包括流涎过多、震颤、共济失调和卧地不起。患病母羊明显低钙血症和氮血症。尿液中未观察到草酸盐晶体。2只急性死亡的母羊死后大体病变轻微且无诊断价值,但在中毒第三天实施安乐死的母羊中可清楚观察到肾周水肿和肾小管变性。草酸盐中毒的诊断通过组织病理学检查结果得以证实。酸模属植物样本干重基础上含有6.6%至11.1%的草酸,该浓度与其他已导致急性草酸盐中毒的含草酸盐植物中的浓度相当。