Cossu M, Riva A, Lantini M S
Dipartimento di Citomorfologia, Universita' di Cagliari, Italia.
J Histochem Cytochem. 1990 Aug;38(8):1165-72. doi: 10.1177/38.8.2365990.
We investigated the subcellular localization of ABH antigens in human submandibular, sublingual, and buccal glands by applying a post-embedding immunogold method using monoclonal antibodies specific for A, B, and H antigens. In most glands the immunoreactivity was usually restricted to mucous cells, in which only secretory granules and sometimes Golgi cisternae were specifically labeled. A and B antigens were demonstrated only in the glands of type A, B, and AB subjects, while H antigen was visualized in glands from individuals of all blood types. Moreover, differences were observed in the relative distribution of ABH antigens, depending on the type of gland.
我们通过使用针对A、B和H抗原的单克隆抗体的包埋后免疫金法，研究了ABH抗原在人类下颌下腺、舌下腺和颊腺中的亚细胞定位。在大多数腺体中，免疫反应性通常局限于黏液细胞，其中只有分泌颗粒，有时还有高尔基池被特异性标记。A和B抗原仅在A型、B型和AB型受试者的腺体中被检测到，而H抗原在所有血型个体的腺体中都能观察到。此外，根据腺体类型的不同，ABH抗原的相对分布也存在差异。
