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[川崎病综述:1977年1月至2012年5月在墨西哥发表文章的视角]

[A review of Kawasaki disease, a perspective from the articles published in Mexico since January 1977 to May 2012].

作者信息

Sotelo-Cruz Norberto

机构信息

Departamento de Medicina y Ciencias de la Salud, Universidad de Sonora, Hermosillo, Sonora, México.

出版信息

Arch Cardiol Mex. 2013 Jul-Sep;83(3):214-22. doi: 10.1016/j.acmx.2013.02.004.

Abstract

Kawasaki disease was described in 1967 by Tomisu Kawasaki. It affects children aged between one and 5 years, and it evolves with fever and small vessel vasculitis, which leads to cardiovascular complications, including coronary aneurisms, myocarditis, valve injuries, pericardial effusion and myocardial infarction; eventually involving many others organs. The etiology actually is not well known, as the exactly pathogenic mechanisms; however, now there are important advances. If the clinical signs and symptoms are identify early and the children received treatment with aspirin and intravenous immunoglobulin, the patients evolves without sequels. The Kawasaki disease is an infrequent disease in Mexico.

摘要

川崎病于1967年由川崎富作首次描述。它影响1至5岁的儿童,表现为发热和小血管血管炎,可导致心血管并发症,包括冠状动脉瘤、心肌炎、瓣膜损伤、心包积液和心肌梗死;最终还会累及许多其他器官。其病因及确切的致病机制目前尚不清楚;不过,现在已有重要进展。如果能早期识别临床体征和症状,并让患儿接受阿司匹林和静脉注射免疫球蛋白治疗,患者可无后遗症地康复。川崎病在墨西哥是一种罕见疾病。

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