Department of Neurosurgery, Chiba Rehabilitation Center, Chiba, Japan.
Thromb Res. 2013 Jun;131(6):487-92. doi: 10.1016/j.thromres.2013.04.022. Epub 2013 May 9.
The diagnosis and treatment of deep vein thrombosis/pulmonary embolism (DVT/PE) are important issues not only in acute-care hospitals, but also in rehabilitation hospitals. To test the hypothesis that DVT/PE occurring at rehabilitation hospitals is carried over from acute-care hospitals, we evaluated a method of DVT screening on admission that combined D-dimer (D-D) measurement and compression ultrasound (CUS).
This prospective single-center observational study included 1043 patients who were admitted to our rehabilitation hospital between August 1, 2007, and August 1, 2011, after excluding those meeting the exclusion criteria. We screened patients on admission and observed the occurrence of DVT/PE until discharge.
Of the 1043 patients, 152 (14.6%) had a D-D level of ≥ 3.0 μg/mL on admission. CUS was performed for these patients and indicated the presence of DVT in 15 patients (1.4%), who were subsequently treated. Of these 15 patients, six (40%) had no DVT symptoms, and five of these six patients had spinal cord injury. Of 137 patients who were CUS negative, two developed DVT/PE within 8 days of hospitalization, and recovery was achieved by treatment. No subsequent occurrence was observed.
These results indicated all cases were carried over from acute-care hospitals. Six out of 15 patients had no symptoms of DVT/PE. Thus, this method of DVT screening on admission to a rehabilitation hospital is useful for risk management.
深静脉血栓形成/肺栓塞(DVT/PE)的诊断和治疗不仅是急性护理医院的重要问题,也是康复医院的重要问题。为了验证在康复医院发生的 DVT/PE 是从急性护理医院转移过来的假设,我们评估了一种在入院时结合 D-二聚体(D-D)测量和压缩超声(CUS)进行 DVT 筛查的方法。
这项前瞻性单中心观察性研究纳入了 2007 年 8 月 1 日至 2011 年 8 月 1 日期间因排除排除标准而入住我院康复科的 1043 例患者。我们在入院时对患者进行筛查,并观察 DVT/PE 的发生情况,直至出院。
在 1043 例患者中,有 152 例(14.6%)在入院时 D-D 水平≥3.0μg/mL。对这些患者进行了 CUS,结果显示 15 例(1.4%)患者存在 DVT,并随后进行了治疗。在这 15 例患者中,有 6 例(40%)没有 DVT 症状,其中 5 例患者患有脊髓损伤。在 137 例 CUS 阴性的患者中,有 2 例在住院后 8 天内发生 DVT/PE,经治疗后痊愈。此后未再发生。
这些结果表明所有病例均从急性护理医院转移而来。15 例患者中有 6 例没有 DVT/PE 的症状。因此,这种在康复医院入院时进行 DVT 筛查的方法有助于进行风险管理。