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睡眠相关内收性喉 dystonia 导致睡眠呼吸暂停:一种睡眠相关呼吸障碍,通过睡眠内窥镜诊断,并使用肉毒毒素治疗。

Sleep-related adductor laryngeal dystonia causing sleep apnea: a sleep-related breathing disorder diagnosed with sleep endoscopy and treated with botulinum toxin.

机构信息

Department of Neurosciences, Institute of Otolaryngology, Padova University, Padova, Italy.

出版信息

Laryngoscope. 2013 Jun;123(6):1560-3. doi: 10.1002/lary.23708. Epub 2013 May 10.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a chronic condition, characterized by recurrent episodes of upper airway collapse during sleep, which affects up to 5% of adults in the Western population. The muscle tone of the human body ordinarily relaxes during sleep, thus causing airway obstruction and leading to sleep apnea. We report a case of a 68-years old male in which dystonic closure of the larynx during sleep caused OSAS. The sleep endoscopy was crucial in establishing the diagnosis of laryngeal dystonia. A botulinum toxin injection in the vocal cord improved the OSAS. These findings define a novel sleep-related breathing disorder.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)是一种慢性疾病,其特征是睡眠期间上呼吸道反复塌陷,影响西方人群中多达 5%的成年人。人体的肌肉张力在睡眠期间通常会放松,从而导致气道阻塞并导致睡眠呼吸暂停。我们报告了一例 68 岁男性病例,其中睡眠时喉痉挛导致 OSAS。睡眠内窥镜检查对于确定喉肌张力障碍的诊断至关重要。声带肉毒毒素注射改善了 OSAS。这些发现定义了一种新的与睡眠相关的呼吸障碍。

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