Hudson Jill, Arnason Thomas, Merrimen Jennifer L O, Lawen Joseph
Department of Urology, Queen Elizabeth II Health Sciences Centre, Halifax, NS;
Can Urol Assoc J. 2013 Jan-Feb;7(1-2):E138-42. doi: 10.5489/cuaj.257.
Intestinal type villous adenomas are uncommon in the genitourinary tract. Most reported cases have been located in the urinary bladder or urachus. Villous adenoma arising in the renal pelvis or ureter is very rare. We present a case of an 81-year-old female who presented with difficulty voiding and mucosuria. A computed tomography scan identified right-sided hydronephrosis, renal parenchymal atrophy, nonobstructing calculi and a lower pole renal mass. She underwent open right nephrectomy. Histopathologic examination of the kidney revealed an intestinal type villous adenoma of the renal pelvis with high-grade dysplasia and focal areas suspicious for invasive adenocarcinoma. We review the four previously reported cases of intestinal type villous adenoma in the renal pelvis and discuss diagnosis and management of this unusual neoplasm.
肠道型绒毛状腺瘤在泌尿生殖道中并不常见。大多数报道的病例位于膀胱或脐尿管。发生于肾盂或输尿管的绒毛状腺瘤非常罕见。我们报告一例81岁女性患者,其表现为排尿困难和黏液尿。计算机断层扫描显示右侧肾盂积水、肾实质萎缩、无梗阻性结石及下极肾肿物。她接受了开放性右肾切除术。肾脏的组织病理学检查显示肾盂的肠道型绒毛状腺瘤伴高级别异型增生以及可疑浸润性腺癌的局灶区域。我们回顾了之前报道的4例肾盂肠道型绒毛状腺瘤病例,并讨论了这种罕见肿瘤的诊断和治疗。