MSA ENT Academy Center, Cassino, Italy.
Otolaryngol Head Neck Surg. 2013 Jul;149(1):142-5. doi: 10.1177/0194599813489494. Epub 2013 May 14.
The n10 component of the ocular vestibular evoked myogenic potential (oVEMP) to sound and vibration stimuli is a crossed response that has enhanced amplitude and decreased threshold in patients with CT-verified superior semicircular canal dehiscence (SSCD). However, demonstrating enhanced VEMP amplitude and reduced VEMP thresholds requires multiple trials and can be very time consuming and tiring for patients, so a specific indicator of probable SCD that is fast and not tiring would be preferred. Here we report a 1-trial indicator: that the oVEMP n10 in response to a very high frequency stimulus (4000 Hz), either air-conducted sound (ACS) or bone conducted vibration (BCV), is such a fast indicator of probable SCD. In 22 healthy subjects, oVEMP n10 at 4000 Hz was not detectable; however, in all 22 CT-verified SSCD patients tested, oVEMP n10 responses were clearly present to 4000 Hz to either ACS or BCV stimuli.
眼震性前庭诱发肌源性电位（oVEMP）中 n10 成分对声音和振动刺激的反应是一种交叉反应，在经 CT 证实的上半规管裂（SSCD）患者中，其振幅增强，阈值降低。然而，要证明 VEMP 振幅增强和阈值降低，需要多次试验，这对患者来说非常耗时和疲劳，因此，最好有一种快速且不累人的特定 SCD 可能指标。在这里，我们报告了一个单次试验指标：对非常高频率的刺激（4000 Hz），无论是空气传导声音（ACS）还是骨传导振动（BCV），oVEMP n10 是可能 SCD 的快速指标。在 22 名健康受试者中，4000 Hz 的 oVEMP n10 无法检测到；然而，在所有 22 名经 CT 证实的 SSCD 患者中，oVEMP n10 对 ACS 或 BCV 刺激的反应在 4000 Hz 时均清晰存在。
