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Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and resistant basal carcinomas in Gorlin syndrome.

作者信息

Chang Anne Lynn S, Atwood Scott X, Tartar Danielle M, Oro Anthony E

出版信息

JAMA Dermatol. 2013 May;149(5):639-41. doi: 10.1001/jamadermatol.2013.30.

Abstract
摘要

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本文引用的文献

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Initial assessment of tumor regrowth after vismodegib in advanced Basal cell carcinoma.
Arch Dermatol. 2012 Nov;148(11):1324-5. doi: 10.1001/archdermatol.2012.2354.
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Efficacy and safety of vismodegib in advanced basal-cell carcinoma.
N Engl J Med. 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713.
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Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation.
J Cell Biol. 2011 Jun 27;193(7):1275-88. doi: 10.1083/jcb.201009126.
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Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.
Sci Transl Med. 2010 Sep 29;2(51):51ra70. doi: 10.1126/scitranslmed.3001599.
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Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma.
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