Department of Urology, University of California, San Francisco, San Francisco, CA, USA.
J Sex Med. 2014 Jan;11(1):75-83. doi: 10.1111/jsm.12201. Epub 2013 May 16.
Mental health disorders are prevalent in the United States, Iraq, and Afghanistan war veterans. Mental illness, including posttraumatic stress disorder (PTSD) with or without psychiatric medications, can increase the risk for male sexual dysfunction, threatening quality of life.
We sought to determine the prevalence and correlates of sexual dysfunction among male Iraq and Afghanistan veterans.
We performed a retrospective cohort study of 405,275 male Iraq and Afghanistan veterans who were new users of U.S. Department of Veterans Affairs healthcare from October 7, 2001 to September 30, 2009 and had 2-year follow-up.
We determined the independent association of mental health diagnoses and sexual dysfunction after adjusting for sociodemographic and military service characteristics, comorbidities, and medications.
Veterans with PTSD were more likely to have a sexual dysfunction diagnosis, be prescribed medications for sexual dysfunction, or both (10.6%), compared with veterans having a mental diagnosis other than PTSD (7.2%), or no mental health diagnosis (2.3%). In a fully adjusted model, PTSD increased the risk of sexual dysfunction by more than threefold (adjusted risk ratio = 3.61, 95% CI = 3.48-3.75). Veterans with mental health disorders, particularly PTSD, were at the highest risk of sexual dysfunction when prescribed psychiatric medications (adjusted risk ratio = 4.59, 95% CI = 4.41-4.77).
Among U.S. combat veterans, mental health disorders, particularly PTSD, increased the risk of sexual dysfunction independent of the use of psychiatric medications.
精神健康障碍在美国、伊拉克和阿富汗退伍军人中普遍存在。精神疾病,包括创伤后应激障碍(PTSD)和/或使用精神科药物,会增加男性性功能障碍的风险,威胁生活质量。
我们旨在确定伊拉克和阿富汗男性退伍军人性功能障碍的流行率和相关因素。
我们对 405275 名美国退伍军人事务部医疗保健的新使用者进行了回顾性队列研究,这些退伍军人在 2001 年 10 月 7 日至 2009 年 9 月 30 日期间开始使用,并进行了 2 年随访。
我们确定了心理健康诊断与性功能障碍之间的独立关联,调整了社会人口统计学和兵役特征、合并症和药物治疗等因素。
与患有 PTSD 以外的其他精神疾病诊断(7.2%)或无精神健康诊断(2.3%)的退伍军人相比,患有 PTSD 的退伍军人更有可能被诊断为性功能障碍、被开具性功能障碍药物治疗处方、或两者兼有(10.6%)。在完全调整的模型中,PTSD 使性功能障碍的风险增加了三倍以上(调整后的风险比=3.61,95%CI=3.48-3.75)。患有精神健康障碍,尤其是 PTSD 的退伍军人在服用精神科药物时性功能障碍的风险最高(调整后的风险比=4.59,95%CI=4.41-4.77)。
在美国作战退伍军人中,精神健康障碍,尤其是 PTSD,增加了性功能障碍的风险,独立于精神科药物的使用。