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前列腺近距离放射治疗后局部晚期症状性阴茎肉瘤复发的手术治疗。

Surgical management of a locally advanced symptomatic recurrence of penile sarcoma secondary to prostate brachytherapy.

机构信息

Department of Genitourinary Oncology, Moffitt Cancer Center and Department of Urology, University of South Florida, Tampa, FL, USA.

出版信息

Int Braz J Urol. 2013 Mar-Apr;39(2):293-4. doi: 10.1590/S1677-5538.IBJU.2013.02.21.

Abstract

UNLABELLED

The surgical management of patients with symptomatic metastatic or locally advanced recurrences involving the penis remains poorly characterized. The aim of the present abstract and video is to detail our experience in the surgical management of a specific patient with a locally advanced symptomatic recurrence of penile sarcoma secondary to prostate cancer treated with primary brachytherapy.

MATERIALS AND METHODS

A 70 year old male patient initially treated for localized prostate cancer with interstitial brachytherapy at an outside facility developed an unfortunate secondary malignancy consisting of a locally advanced penile sarcoma involving as well the prostate and base of the bladder. Despite our best efforts to control his pain, he developed a very symptomatic local recurrence with a secondary penile abscess and purulent periurethral drainage. At this time, it was felt a surgical resection consisting of a total penectomy, urethrectomy, cystoprostatectomy, and ileal conduit urinary diversion would be the best option for local cancer control in this particular patient.

RESULTS

The patient underwent the surgical resection without any complications as illustrated in this surgical video, with a jejunal intestinal mass identified at the time of surgery which was resected with a primary bowel anastomosis performed. The patient was discharged from hospital uneventfully with his symptomatic local recurrence being successfully managed and the patient no longer requiring oral narcotics for pain control. The pathological report confirmed a locally advanced sarcoma involving the penile, prostate, and bladder which was resected with negative surgical margins and the jejunal mass was confirmed to represent a small bowel sarcoma metastatic site.

CONCLUSION

As highlighted in the present video, the treatment of a symptomatic sarcoma local recurrence contiguously involving the penis can be successfully managed provided the patient is informed of the potential morbidity and psychosocial implications imparted by performing a total penectomy and adjacent organ resection.

摘要

目的

本摘要和视频旨在详细介绍我们对一名特殊患者的手术治疗经验,该患者因前列腺癌接受原发近距离放射治疗后出现局部晚期阴茎肉瘤的症状性复发。

材料和方法

一名 70 岁男性患者最初在一家外部机构接受局部前列腺癌的间质近距离放射治疗,随后发展出一种不幸的继发性恶性肿瘤,包括局部晚期阴茎肉瘤,累及前列腺和膀胱底部。尽管我们尽力控制他的疼痛,但他仍出现了非常症状性的局部复发,伴有继发性阴茎脓肿和脓性尿道周围引流。此时,我们认为对该特定患者进行包括全阴茎切除术、尿道切除术、膀胱前列腺切除术和回肠造口术的尿流改道术的手术切除是局部癌症控制的最佳选择。

结果

患者在无任何并发症的情况下接受了手术切除,正如手术视频所示,并在手术时发现了一个空肠肠段肿块,行一期肠吻合术切除。患者顺利出院,症状性局部复发得到成功控制,患者不再需要口服麻醉药物来控制疼痛。病理报告证实了一种局部晚期肉瘤累及阴茎、前列腺和膀胱,已通过手术切除并获得阴性切缘,空肠肿块被确认为小肠道肉瘤的转移部位。

结论

正如本视频所强调的,对于连续累及阴茎的症状性肉瘤局部复发,如果患者了解到进行全阴茎切除术和相邻器官切除术所带来的潜在发病率和社会心理影响,这种疾病可以得到成功治疗。

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