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梅克尔憩室自发性穿孔:病例报告及文献复习

Spontaneous perforation of Meckel's diverticulum: case report and review of literature.

作者信息

Grasso Emanuele, Politi Antonio, Progno Valerio, Guastella Tommaso

机构信息

Department of General Surgery, Clinic Santa Maria Hospital, Bari, Italy.

出版信息

Ann Ital Chir. 2013 May 20;84(ePub):S2239253X13020902.

Abstract

AIMS

Meckel's diverticulum is a congenital anomaly found in approximately 2% of the general population. The complications caused by Meckel's diverticulum include intussusception, volvulus in adolescents and acute bleeding in adults 3. This is an interesting and unusual case of spontaneous perforation of Meckel's diverticulum, in a Caucasian woman.

METHODS

A 46-year-old Caucasian woman was admitted because of severe abdominal pain and diarrhoea. A CT (Fig. 1) scan of the abdomen and pelvis was obtained, which demonstrated free air and a moderate amount of free fluid in the pelvis tracking up the gutters. The patient was consented and taken to theatre for diagnostic laparoscopy. A normal appendix was identified during laparoscopic examination of the abdomen. An inflammatory mass was seen with turbid fluid collection in the pelvic area on laparoscopy. The inflammatory mass turned out to be a perforated Meckel's diverticulum (Fig. 2). Wedge resection of the perforated Meckel's diverticulum was performed with endoGIA stapler fired at the base of diverticulum. Histopathology showed heterotopic gastric mucosa within the diverticulum and evidence of acute inflammation with perforation. The patient was followed up for two years and is symptom-free.

DISCUSSION

The total lifetime rate of complications is widely accepted at 4%, with a male-to female ratio ranging from 1.8:1 to 3:1 4,5. Hemorrhage is the most common presentation in children and is reported in over 50% of cases 10. In adults, hemorrhage occurs often but only in 11.8% is present 5. 90% of bleeding diverticula contain heterotropic mucosa, most often gastric mucosa 13. In one study, 11% of children with complicated Meckel's diverticulum (MD) were initially diagnosed with appendicitis.8

CONCLUSIONS

The diagnosis of ruptured MD was ultimately made by laparoscopy. This case demonstrates that a healthy degree of suspicion for complicated MD should be present when dealing with a questionable diagnosis of appendicitis. Laparoscopy has a definite role in patients with symptomatic Meckel's diverticulum, especially when the diagnosis is in doubt and it has proved definitive in facilitating diagnosis.

摘要

目的

梅克尔憩室是一种先天性异常,在普通人群中的发生率约为2%。梅克尔憩室引起的并发症包括肠套叠、青少年肠扭转和成人急性出血。这是一例关于一名白种女性梅克尔憩室自发穿孔的有趣且罕见的病例。

方法

一名46岁的白种女性因严重腹痛和腹泻入院。进行了腹部和盆腔的CT(图1)扫描,结果显示盆腔内有游离气体和中等量的游离液体沿肠沟向上蔓延。患者签署知情同意书后被送往手术室进行诊断性腹腔镜检查。在腹腔镜检查腹部时发现阑尾正常。腹腔镜检查时在盆腔区域可见一个炎性肿块,伴有浑浊液体聚集。结果发现该炎性肿块是一个穿孔的梅克尔憩室(图2)。使用内镜切割吻合器在憩室底部进行穿孔梅克尔憩室的楔形切除术。组织病理学显示憩室内有异位胃黏膜以及急性炎症伴穿孔的证据。对该患者进行了两年的随访,其无症状。

讨论

并发症的终生总发生率普遍认为是4%,男女比例在1.8:1至3:1之间。出血是儿童中最常见的表现,在超过50%的病例中会出现。在成人中,出血也经常发生,但仅占11.8%。90%的出血性憩室含有异位黏膜,最常见的是胃黏膜。在一项研究中,11%患有复杂梅克尔憩室(MD)的儿童最初被诊断为阑尾炎。

结论

梅克尔憩室破裂的诊断最终通过腹腔镜检查得以明确。该病例表明,在处理可疑的阑尾炎诊断时,应高度怀疑复杂的梅克尔憩室。腹腔镜检查在有症状的梅克尔憩室患者中具有明确作用,尤其是在诊断存疑时,并且已证明其在促进诊断方面具有决定性作用。

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