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先天性心脏病合并室上性心动过速消融的当代结果:单中心 116 例患者的经验。

Contemporary outcomes of supraventricular tachycardia ablation in congenital heart disease: a single-center experience in 116 patients.

机构信息

Cardiac Morphology Unit, Department of Pediatrics, Royal Brompton Hospital, London, United Kingdom.

出版信息

Circ Arrhythm Electrophysiol. 2013 Jun;6(3):606-13. doi: 10.1161/CIRCEP.113.000415. Epub 2013 May 17.

Abstract

BACKGROUND

Remote magnetic navigation-guided ablation with 3-dimensional (3D)-image integration could provide maximum benefit in patients with complex anatomy. We reviewed supraventricular tachycardia (SVT) ablation in adult patients with congenital heart disease to assess the contribution of these technologies.

METHODS AND RESULTS

One hundred fifty-four SVT ablation procedures (228 SVTs) using a 3D-electroanatomic mapping system in 116 adult patients with congenital heart disease (mean age, 41; 76 male) were classified into 3 groups: Group A, manual mapping/ablation (n=60 procedures); Group B, remote magnetic navigation-guided mapping/ablation with normal femoral vein access (49); and Group C, remote magnetic navigation-guided mapping/ablation with difficult access (45). Group A included simple anomalies with less SVTs. Group B comprised predominantly Fontan patients with more SVTs. Group C included more complex defects, such as intra-atrial baffle or interrupted inferior venous access, in which retrograde aortic and superior venous accesses were used exclusively with more frequent use of image integration (97.8%; P<0.001). Acute success was 91.5%, 83.7%, and 82.2%, respectively (P=0.370). In group C, fluoroscopy time was the shortest (median, 4.2 min; P<0.001) despite the longer procedure duration (median, 253 min; P<0.001). SVTs free rates were 80.4%, 82.4%, and 75.8%, respectively (P=0.787) during a mean 20-months follow-up period.

CONCLUSIONS

The combination of remote magnetic navigation, 3D-image integration, and electroanatomic mapping system facilitated safe and feasible ablation with very low fluoroscopy exposure even in patients with complex anomalies.

摘要

背景

远程磁导航引导下的三维(3D)图像融合消融术可为复杂解剖结构的患者带来最大益处。我们回顾了成人先天性心脏病患者的室上性心动过速(SVT)消融术,以评估这些技术的贡献。

方法和结果

在 116 例成人先天性心脏病患者(平均年龄 41 岁;76 例男性)中,使用三维电生理标测系统进行了 154 次 SVT 消融术(228 次 SVTs),分为 3 组:A 组,手动标测/消融(n=60 次);B 组,远程磁导航引导下的标测/消融,采用正常股静脉入路(49 次);C 组,远程磁导航引导下的标测/消融,采用困难入路(45 次)。A 组包括简单畸形伴较少 SVTs。B 组主要为 Fontan 患者,SVTs 较多。C 组包括更复杂的缺陷,如房间隔缺损或下腔静脉中断,仅使用逆行主动脉和上腔静脉入路,更频繁地使用图像融合(97.8%;P<0.001)。急性成功率分别为 91.5%、83.7%和 82.2%(P=0.370)。在 C 组中,尽管手术时间较长(中位数 253 分钟;P<0.001),但透视时间最短(中位数 4.2 分钟;P<0.001)。在平均 20 个月的随访期间,SVTs 无复发率分别为 80.4%、82.4%和 75.8%(P=0.787)。

结论

即使在复杂畸形患者中,远程磁导航、3D 图像融合和电生理标测系统的结合也能安全、可行地进行消融术,且透视辐射暴露极低。

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