Harari Joseph
Veterinary Surgical Specialists, 21 East Mission Avenue, Spokane,WA 99202, USA.
Compend Contin Educ Vet. 2008 Oct;30(10):E7.
In this retrospective study of cases from Italy and Switzerland, the clinical features of injection-site sarcomas in 57 cats were reviewed. In addition to routine physical, laboratory, and radiographic examinations, advanced imaging (computed tomographic scans) was conducted to delineate tumor extent. Treatment was by wide surgical excision including partial scapulectomy, spinous process removal, and amputation (appendicular lesions). Radiotherapy and chemotherapy were also used. The results revealed that cats with grade 3 tumors were most likely to develop distant pulmonary metastases (and to have shorter survival rates); this occurred in 21% of the cases.Median follow-up for cats that survived (51%) was 600 days; for those that died (49%), it was 272 days. In this study, tumor size, as measured manually by calipers, was not a prognostic factor. Furthermore, factors associated with local recurrence were not identified. The authors recognized the limitations of a retrospective study, especially with regard to treatments before referral.
在这项针对来自意大利和瑞士病例的回顾性研究中,对57只猫注射部位肉瘤的临床特征进行了回顾。除了常规的体格检查、实验室检查和放射检查外,还进行了先进的成像检查(计算机断层扫描)以确定肿瘤范围。治疗方法为广泛的手术切除,包括部分肩胛骨切除术、棘突切除术和截肢术(四肢病变)。还使用了放疗和化疗。结果显示,3级肿瘤的猫最有可能发生远处肺转移(且生存率较低);21%的病例出现了这种情况。存活猫(51%)的中位随访时间为600天;死亡猫(49%)的中位随访时间为272天。在本研究中,用卡尺手动测量的肿瘤大小不是一个预后因素。此外,未发现与局部复发相关的因素。作者认识到回顾性研究的局限性,特别是关于转诊前的治疗方面。