Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5407, USA.
Eur J Vasc Endovasc Surg. 2013 Aug;46(2):175-90. doi: 10.1016/j.ejvs.2013.04.029. Epub 2013 May 28.
OBJECTIVE/BACKGROUND: Classification systems for aortic dissection provide important guides to clinical decision-making, but the relevance of traditional categorization schemes is being questioned in an era when endovascular techniques are assuming a growing role in the management of this frequently complex and catastrophic entity. In recognition of the expanding range of interventional therapies now used as alternatives to conventional treatment approaches, the Working Group on Aortic Diseases of the DEFINE Project developed a categorization system that features the specific anatomic and clinical manifestations of the disease process that are most relevant to contemporary decision-making.
The DISSECT classification system is a mnemonic-based approach to the evaluation of aortic dissection. It guides clinicians through an assessment of six critical characteristics that facilitate optimal communication of the most salient details that currently influence the selection of a therapeutic option, including those findings that are key when considering an endovascular procedure, but are not taken into account by the DeBakey or Stanford categorization schemes. The six features of aortic dissection include: duration of disease; intimal tear location; size of the dissected aorta; segmental extent of aortic involvement; clinical complications of the dissection, and thrombus within the aortic false lumen.
In current clinical practice, endovascular therapy is increasingly considered as an alternative to medical management or open surgical repair in select cases of type B aortic dissection. Currently, endovascular aortic repair is not used for patients with type A aortic dissection, but catheter-based techniques directed at peripheral branch vessel ischemia that may complicate type A dissection are considered valuable adjunctive interventions, when indicated. The use of a new system for categorization of aortic dissection, DISSECT, addresses the shortcomings of well-known established schemes devised more than 40 years ago, before the introduction of endovascular techniques. It will serve as a guide to support a critical analysis of contemporary therapeutic options and inform management decisions based on specific features of the disease process.
目的/背景:主动脉夹层分类系统为临床决策提供了重要指导,但在腔内技术在管理这种经常复杂和灾难性疾病中发挥越来越大作用的时代,传统分类方案的相关性受到质疑。认识到现在用于替代传统治疗方法的介入治疗方法范围不断扩大,DEFINE 项目的主动脉疾病工作组开发了一种分类系统,其特点是与当代决策最相关的疾病过程的具体解剖和临床表现。
DISSECT 分类系统是一种基于记忆的主动脉夹层评估方法。它指导临床医生评估六个关键特征,有助于最佳沟通当前影响治疗选择的最突出细节,包括在考虑腔内手术时很关键但 DeBakey 或 Stanford 分类方案不考虑的那些发现。主动脉夹层的六个特征包括:疾病持续时间;内膜撕裂部位;夹层主动脉的大小;主动脉受累的节段范围;夹层的临床并发症和主动脉假腔中的血栓。
在当前的临床实践中,腔内治疗越来越多地被认为是选择病例的 B 型主动脉夹层的替代药物治疗或开放手术修复。目前,腔内主动脉修复不用于 A 型主动脉夹层患者,但用于治疗可能使 A 型夹层复杂化的外周分支血管缺血的导管技术被认为是有价值的辅助干预措施,当有指征时。一种新的主动脉夹层分类系统 DISSECT 的使用解决了 40 多年前在腔内技术引入之前制定的著名既定方案的缺点。它将作为支持对当代治疗选择进行批判性分析的指南,并根据疾病过程的具体特征为管理决策提供信息。