Jain Sunila, Jain Kanika, Chopra Prem
Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
Int J Gynecol Pathol. 2013 Jul;32(4):421-5. doi: 10.1097/PGP.0b013e31826a646a.
Rhabdomyosarcoma (RMS) of the cervix in women older than 40 years of age is extremely rare. Embryonal RMS can appear deceptively benign both clinically and histopathologically. Diagnosis is made on the basis of histomorphologic and immunohistochemical findings. A high index of suspicion is, however, needed to make the diagnosis, as they can masquerade as benign polyps. A 41-year-old female with cervical RMS is described here. The initial biopsy diagnosis of embryonal RMS was confirmed on subsequent hysterectomy. The present case report is described with emphasis on histopathologic features and diagnostic difficulties along with a brief review of the literature.
40岁以上女性宫颈横纹肌肉瘤(RMS)极为罕见。胚胎性RMS在临床和组织病理学上可能看似良性。诊断基于组织形态学和免疫组化结果。然而,由于它们可能伪装成良性息肉,因此需要高度怀疑才能做出诊断。本文描述了一名41岁患有宫颈RMS的女性。最初活检诊断为胚胎性RMS,随后子宫切除术中得到证实。本病例报告重点描述了组织病理学特征和诊断难点,并对文献进行了简要回顾。