孕中期子宫动脉多普勒测速法对高危和低危女性先兆子痫的预测
Prediction of preeclampsia by midtrimester uterine artery Doppler velocimetry in high-risk and low-risk women.
作者信息
Bhattacharyya Sanjoy Kumar, Kundu Sarmila, Kabiraj Sankar Prasad
机构信息
Department of Gynecology & Obstetrics, North Bengal Medical College, Darjeeling, India.
出版信息
J Obstet Gynaecol India. 2012 Jun;62(3):297-300. doi: 10.1007/s13224-012-0219-8. Epub 2012 Aug 17.
OBJECTIVE
To observe the role of uterine artery Doppler flow velocimetry at midtrimester in prediction of preeclampsia.
METHOD
179 women carrying <16 weeks of pregnancy, with singleton fetus and without any fetal anomaly were recruited and were divided in high-risk and low-risk group. Doppler velocimetry of uterine artery was done at 24-26 weeks. Any notch in uterine artery, unilateral or bilateral, or RI > 0.6, was considered abnormal. Women were followed up and development of preeclampsia noted.
RESULT
Sensitivity and specificity of abnormal uterine artery Doppler study for prediction of preeclampsia were 73.33 and 86.48 % in high-risk and 57.14 and 95.83 % in low-risk group, respectively. Relative risk with 95 % confidence interval was 5.427 (2.272-12.958) in high-risk and 13.65 (5.669-32.865) in low-risk women.
CONCLUSION
Doppler velocimetry of uterine artery at 24 weeks can be used as a reliable screening test for prediction of preeclampsia in both high-risk and low-risk women.
目的
观察孕中期子宫动脉多普勒血流测速在预测子痫前期中的作用。
方法
招募179例妊娠<16周、单胎且无任何胎儿异常的孕妇，分为高危组和低危组。在孕24 - 26周进行子宫动脉多普勒测速。子宫动脉出现任何切迹（单侧或双侧）或阻力指数（RI）>0.6均视为异常。对孕妇进行随访并记录子痫前期的发生情况。
结果
子宫动脉多普勒检查异常预测子痫前期的敏感度和特异度在高危组分别为73.33%和86.48%，在低危组分别为57.14%和95.83%。高危组95%置信区间的相对危险度为5.427（2.272 - 12.958），低危组为13.65（5.669 - 32.865）。
结论
孕24周时子宫动脉多普勒测速可作为预测高危和低危孕妇子痫前期的可靠筛查试验。
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