Russell Leslie, Stockwell Philip
Internal medicine resident at The Warren Alpert Medical School at Brown University.
R I Med J (2013). 2013 Jun 4;96(6):33-5.
The classic finding of Takotsubo's cardiomyopathy is left ventricular systolic dysfunction with echocardiographic evidence of apical ballooning in the absence of significant coronary disease. Intracranial hemorrhage is a known cause for stress-induced cardiomyopathy with a similar echocardiographic presentation. This diagnostic finding suggests a similar pathophysiologic mechanism between neurogenic cardiac damage and the wide array of medical and psychosocial disorders that are known to cause stress-induced cardiomyopathy (Takotsubo's syndrome). The neurogenic-cardiac variant of stress-induced cardiomyopathy is associated with good cardiovascular prog- nosis; the hallmark feature of the disorder is complete echocardiographic resolution of systolic dysfunction within a short period of time. While malignant presentations are rare, the disorder can present as severe heart failure or ventricular tachyarrhythmias. We report a case of a near life-threatening episode of polymorphic ventricular tachycardia due to a subarachnoid hemorrhage (SAH)-induced stress-cardiomyopathy.
应激性心肌病的典型表现是左心室收缩功能障碍,超声心动图显示心尖部气球样变,且无明显冠状动脉疾病。颅内出血是应激性心肌病的已知病因,其超声心动图表现相似。这一诊断结果提示,神经源性心脏损伤与已知可导致应激性心肌病(应激性心肌病综合征)的多种医学和社会心理障碍之间存在相似的病理生理机制。应激性心肌病的神经源性心脏变异型与良好的心血管预后相关;该疾病的标志性特征是收缩功能障碍在短时间内通过超声心动图完全恢复。虽然恶性表现罕见,但该疾病可表现为严重心力衰竭或室性快速心律失常。我们报告一例因蛛网膜下腔出血(SAH)诱发的应激性心肌病导致的多形性室性心动过速,险些危及生命。