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中低收入国家的母婴营养不足和超重问题。

Maternal and child undernutrition and overweight in low-income and middle-income countries.

机构信息

Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.

Universidade Federal de Pelotas, Pelotas, Rio Grande do Sol, Brazil.

出版信息

Lancet. 2013 Aug 3;382(9890):427-451. doi: 10.1016/S0140-6736(13)60937-X. Epub 2013 Jun 6.

Abstract

Maternal and child malnutrition in low-income and middle-income countries encompasses both undernutrition and a growing problem with overweight and obesity. Low body-mass index, indicative of maternal undernutrition, has declined somewhat in the past two decades but continues to be prevalent in Asia and Africa. Prevalence of maternal overweight has had a steady increase since 1980 and exceeds that of underweight in all regions. Prevalence of stunting of linear growth of children younger than 5 years has decreased during the past two decades, but is higher in south Asia and sub-Saharan Africa than elsewhere and globally affected at least 165 million children in 2011; wasting affected at least 52 million children. Deficiencies of vitamin A and zinc result in deaths; deficiencies of iodine and iron, together with stunting, can contribute to children not reaching their developmental potential. Maternal undernutrition contributes to fetal growth restriction, which increases the risk of neonatal deaths and, for survivors, of stunting by 2 years of age. Suboptimum breastfeeding results in an increased risk for mortality in the first 2 years of life. We estimate that undernutrition in the aggregate--including fetal growth restriction, stunting, wasting, and deficiencies of vitamin A and zinc along with suboptimum breastfeeding--is a cause of 3·1 million child deaths annually or 45% of all child deaths in 2011. Maternal overweight and obesity result in increased maternal morbidity and infant mortality. Childhood overweight is becoming an increasingly important contributor to adult obesity, diabetes, and non-communicable diseases. The high present and future disease burden caused by malnutrition in women of reproductive age, pregnancy, and children in the first 2 years of life should lead to interventions focused on these groups.

摘要

中低收入国家的母婴营养不良包括营养不足以及超重和肥胖问题日益严重。过去二十年,低体重指数(表明母体营养不足)有所下降,但在亚洲和非洲仍很普遍。自 1980 年以来,母体超重的比例稳步上升,在所有地区均超过体重不足。过去二十年,5 岁以下儿童线性生长迟缓的流行率有所下降,但在南亚和撒哈拉以南非洲地区的流行率高于其他地区,全球至少有 1.65 亿儿童受到影响;2011 年,5200 多万儿童消瘦。维生素 A 和锌的缺乏会导致死亡;碘和铁缺乏以及发育迟缓可能导致儿童无法发挥其发展潜力。母体营养不足会导致胎儿生长受限,增加新生儿死亡风险,对于幸存者来说,2 岁时的生长迟缓风险增加。母乳喂养不足会增加生命最初两年的死亡率。我们估计,营养不良(包括胎儿生长受限、发育迟缓、消瘦、维生素 A 和锌缺乏以及母乳喂养不足)每年导致 310 万儿童死亡,占 2011 年所有儿童死亡的 45%。母体超重和肥胖会增加母体发病率和婴儿死亡率。儿童超重正日益成为成年肥胖、糖尿病和非传染性疾病的重要原因。目前和未来育龄妇女、妊娠妇女以及生命最初 2 年的儿童的营养不良造成的高疾病负担应导致针对这些群体的干预措施。

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