Schietroma Mario, De Vita Fabiola, Carlei Francesco, Leardi Sergio, Pessia Beatrice, Sista Federico, Amicucci Gianfranco
Department of Surgery, University of L'Aquila, Italy.
Surg Laparosc Endosc Percutan Tech. 2013 Jun;23(3):281-5. doi: 10.1097/SLE.0b013e31828e3954.
There are few published reports on the outcomes of ≥ 10 years after a laparoscopic floppy Nissen fundoplication (LFNF).
From April 1994 to January 2012, 567 patients underwent LFNF and the outcomes of 211 cases were determined (from April 1994 to October 2000).
Outcomes at ≥ 11 years after surgery was available for 178 patients (84.3%) of which 167 (93.8%) had no heartburn or mild heartburn, 8 (4.5%) had moderate heartburn, and 3 had (1.7%) severe heartburn. Dysphagia was nonexistent or mild in 153 (85.9%), whereas the remaining 14.1% presented moderate to severe symptoms. Reports of 69.1% patients showed none or mild symptoms of abdominal bloating, that of 23% patients showed moderate discomfort, and reports of 7.8% showed severe bloating. Satisfaction score was 8.6 (of 10). A further surgical procedure was required for 7 patients (3.9%): 4 for recurrent reflux and 3 for dysphagia (2 for a tight wrap and 1 for a tight esophageal hiatus). Postoperative dysphagia sufficient for an endoscopic dilatation was observed in 4 patients (2.3%), where 3 were successfully managed with a single dilatation procedure and the last patient underwent several dilatations before adequate swallowing.
LFNF is an effective long-term treatment for gastroesophageal reflux disease, yielding similar results to open fundoplication.
关于腹腔镜下松弛性nissen胃底折叠术(LFNF)术后10年以上疗效的公开报道较少。
1994年4月至2012年1月,567例患者接受了LFNF手术,确定了其中211例患者的疗效(1994年4月至2000年10月)。
178例患者(84.3%)有术后11年以上的随访结果,其中167例(93.8%)无烧心或有轻度烧心,8例(4.5%)有中度烧心,3例(1.7%)有重度烧心。153例(85.9%)不存在吞咽困难或有轻度吞咽困难,其余14.1%有中度至重度症状。69.1%的患者报告无腹胀或有轻度腹胀症状,23%的患者报告有中度不适,7.8%的患者报告有重度腹胀。满意度评分为8.6(满分10分)。7例患者(3.9%)需要再次手术:4例因复发性反流,3例因吞咽困难(2例因胃底折叠过紧,1例因食管裂孔过紧)。4例患者(2.3%)观察到术后吞咽困难严重到需要内镜扩张,其中3例通过单次扩张手术成功治疗,最后1例患者在吞咽功能恢复正常前接受了多次扩张。
LFNF是治疗胃食管反流病的一种有效的长期治疗方法,其疗效与开放性胃底折叠术相似。