Department of Dermatology and Venereology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Clin Exp Dermatol. 2013 Dec;38(8):823-9. doi: 10.1111/ced.12098. Epub 2013 Jun 13.
Photodermatoses are characterized by an abnormal cutaneous response to 'ordinary' light exposure.
To study the spectrum of photodermatoses in populations with dark skin (skin types IV-VI) at a tertiary referral centre.
Consecutive patients with skin lesions confined to or predominantly located on photoexposed parts of the body and/or with photosensitivity were enrolled in the study, and their clinical details were recorded. Diagnosis was made on clinical grounds, and relevant investigations were carried out if required. Patch and photopatch testing were carried out in patients with chronic actinic dermatitis (CAD). Selected patients with CAD also underwent phototesting with UV (ultraviolet) A and broadband UVB light.
We enrolled 362 patients (146 men, 216 women; mean age 35.6 ± 13.6 years), with mean disease duration of 3.4 years. The Fitzpatrick skin types were IV and V (52.8% and 47.2% of patients, respectively). Polymorphic light eruption (PMLE) was the commonest photodermatosis seen, affecting 59.7% of patients, followed by CAD (13.8%), collagen vascular disorders (7.7%), photoaggravated atopic dermatitis (6.1%), actinic lichen planus (ALP; 2.2%) and lichen planus pigmentosus (LPP; 1.6%). The majority (84.5%) of patients were involved in indoor work. Papular PMLE (37%) was the most common variant of PMLE, followed by pinpoint (31%), eczematous (22.2%), lichenoid (5.5%) and plaque-type (4.1%) PMLE.
The spectrum of photodermatoses in Indian patients with dark skin phototypes (IV and V), is similar to that reported from other parts of the world. PMLE was the commonest photodermatosis seen, with the pinpoint and lichenoid variants accounting for over one-third of the PMLE cases. ALP and LPP were also not uncommon in our dark-skinned population.
光皮病的特征是皮肤对“普通”光暴露的异常反应。
在一个三级转诊中心研究深色皮肤（皮肤类型 IV-VI）人群中的光皮病谱。
连续招募有皮肤病变局限于或主要位于光暴露部位和/或光敏性的患者，并记录其临床详细信息。根据临床情况做出诊断，并在需要时进行相关检查。对慢性光化性皮炎（CAD）患者进行斑贴和光斑贴试验。选择患有 CAD 的患者还接受了长波紫外线（UVA）和宽带 UVB 光的光测试。
我们共招募了 362 名患者（146 名男性，216 名女性；平均年龄 35.6±13.6 岁），平均患病时间为 3.4 年。Fitzpatrick 皮肤类型为 IV 型和 V 型（分别占患者的 52.8%和 47.2%）。多形性光疹（PMLE）是最常见的光皮病，影响 59.7%的患者，其次是 CAD（13.8%）、胶原血管疾病（7.7%）、光加重特应性皮炎（6.1%）、光化性扁平苔藓（ALP；2.2%）和色素性扁平苔藓（LPP；1.6%）。大多数（84.5%）患者从事室内工作。丘疹型 PMLE（37%）是 PMLE 最常见的变异型，其次是针尖型（31%）、湿疹型（22.2%）、苔藓样型（5.5%）和斑块型（4.1%）PMLE。
在印度深色皮肤（IV 和 V 型）患者中，光皮病谱与世界其他地区报道的相似。PMLE 是最常见的光皮病，针尖型和苔藓样型占 PMLE 病例的三分之一以上。在我们的深色人群中，ALP 和 LPP 也不罕见。
