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婴儿大型致弱视性眼睑血管瘤先采用肠外皮质类固醇治疗,随后尽早进行手术切除。

Parenteral corticosteroids followed by early surgical resection of large amblyogenic eyelid hemangiomas in infants.

作者信息

Essawy Rania El, Galal Rasha Essameldin

机构信息

Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Clin Ophthalmol. 2013;7:955-8. doi: 10.2147/OPTH.S45351. Epub 2013 May 28.

Abstract

BACKGROUND

The purpose of this study was to evaluate the results and complications of early surgical resection of large amblyogenic subdermal eyelid hemangiomas in infants after prior short-term parenteral administration of corticosteroids.

METHODS

Sixteen infants were given dexamethasone 2 mg/kg/day in two divided doses for three consecutive days prior to scheduled surgical excision of large eyelid hemangiomas. The lesions were accessed via an upper eyelid crease, subeyebrow incision, or a lower eyelid subciliary incision.

RESULTS

In all cases, surgical excision of the entire lesion was possible with no significant intraoperative or postoperative complications. The levator muscle/aponeurosis complex was involved in 31.25% of cases and was managed by reinsertion or repositioning without resection. A satisfactory lid position and contour with immediate clearing of the visual axis was achieved in all but one case (93.8%).

CONCLUSION

Parenteral corticosteroids helped in reducing volume and blood flow from the hemangiomas, allowing for very early total excision of large subdermal infantile hemangiomas without significant intraoperative hemorrhage. This resulted in immediate elimination of any reason for occlusion amblyopia. Long-term follow-up of visual development in these patients would help to demonstrate the effectiveness of this strategy compared with more conservative measures.

摘要

背景

本研究的目的是评估在婴儿短期胃肠外给予皮质类固醇激素后,早期手术切除大型致弱视性皮下眼睑血管瘤的结果及并发症。

方法

在计划对大型眼睑血管瘤进行手术切除前,16例婴儿连续3天每天分两次给予地塞米松2mg/kg。通过上睑皱襞、眉下切口或下睑睫毛下切口处理病变。

结果

所有病例均成功完整切除病变,术中及术后均无明显并发症。31.25%的病例提上睑肌/腱膜复合体受累,通过重新附着或重新定位而非切除进行处理。除1例(93.8%)外,所有病例均获得了满意的眼睑位置和外形,视轴立即清晰。

结论

胃肠外给予皮质类固醇激素有助于减少血管瘤的体积和血流,从而能够在极早期完整切除大型皮下婴儿血管瘤,且术中无明显出血。这立即消除了导致遮盖性弱视的任何原因。对这些患者视觉发育的长期随访将有助于证明与更保守措施相比该策略的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c081/3673960/e0203bd5e44b/opth-7-955f1.jpg

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