剖宫产腹壁瘢痕处子宫内膜异位症恶变：一例报告

Malignant transformation of endometriosis in a cesarean section abdominal wall scar: a case report.

作者信息

Stevens Erin E, Pradhan Tana S, Chak Yvonne, Lee Yi-Chun

机构信息

Division of Gynecologic Oncology, State University of New York (SUNY) Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

出版信息

J Reprod Med. 2013 May-Jun;58(5-6):264-6.

PMID:23763014

Abstract

BACKGROUND

Endometriosis occurring in a cesarean section abdominal wall scar is reported at a rate of 0.03-0.45%. Malignant transformation of this type of endometriosis is exceptionally rare.

CASE

A 51-year-old, G3P2012, Black woman presented with a lump in her cesarean section abdominal wall scar that was increasing in size. Biopsy of the mass revealed metastatic adenocarcinoma with poorly differentiated, nonmucinous ovarian primary. She received 3 cycles of neoadjuvant chemotherapy and underwent an interval debulking with the final pathology showing malignant transformation of endometriosis within her abdominal wall scar. She then completed radiotherapy to the area and is disease-free 6 months later.

CONCLUSION

Our combination of neoadjuvant chemotherapy and excision of the mass with negative margins followed by adjuvant radiotherapy is a feasible treatment option.

摘要

背景

剖宫产腹壁瘢痕处发生子宫内膜异位症的报告发生率为0.03%-0.45%。这种类型的子宫内膜异位症发生恶变极为罕见。

病例

一名51岁、孕3产2（G3P2）、有1次流产史（012）的黑人女性，因剖宫产腹壁瘢痕处出现一个肿块且肿块不断增大前来就诊。对该肿块进行活检，结果显示为转移性腺癌，原发性卵巢为低分化、非黏液性。她接受了3个周期的新辅助化疗，并接受了间隔减瘤手术，最终病理显示腹壁瘢痕内的子宫内膜异位症发生了恶变。随后她完成了该区域的放疗，6个月后无疾病迹象。